Friday, October 23, 2020
Mitochondrial Health

ATP & Respiration: Crash Course Biology #7



In which Hank does some push ups for science and describes the “economy” of cellular respiration and the various processes whereby our bodies create energy in the form of ATP.

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Special thanks go to Stafford Fitness (www.staffordfitness.net) for allowing us to shoot the gym scenes in their facilities.

This video uses sounds from Freesound.org, a list of which can be found, along with the CITATIONS for this episode, in the Google Document here: http://dft.ba/-25Ad

Table of Contents:
1) Cellular Respiration 01:00
2) Adenosine Triphosphate 01:29
3) Glycolysis 4:13
A) Pyruvate Molecules 5:00
B) Anaerobic Respiration/Fermentation 5:33
C) Aerobic Respiration 6:45
4) Krebs Cycle 7:06
A) Acetyl COA 7:38
B) Oxaloacetic Acid 8:21
C) Biolography: Hans Krebs 8:37
D) NAD/FAD 9:48
5) Electron Transport Chain 10:55
6) Check the Math 12:33

TAGS: crashcourse, biology, science, chemistry, energy, atp, adenosine triphosphate, cellular respiration, glucose, adp, hydrolysis, glycolysis, krebs cycle, electron transport chain, fermentation, lactic acid, enzyme, hans krebs, citric acid, ATP synthase Support CrashCourse on Patreon: https://www.patreon.com/crashcourse

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23 thoughts on “ATP & Respiration: Crash Course Biology #7
  1. It's 2020 and my "Science for Teachers" instructor assigned this video and I am a happy nerdfighter for that! Will continue to use these videos in my class as a student and I'll use crash course kids when I have my own classroom one day! šŸ˜€

  2. Can someone help me?!

    If I have 12 NADH from glycolysis, what is the net ATP? and furthermore, how much ATP is produced from 22 NADH during the Krebs cycle?

    This is a question I struggled with in AP. If you solve it please explain how you got the answer.

  3. I formerly worked assisting children with Special Needs in public classrooms. I provided one-to-one assistance to a student who was born with Mitochondria and hydrocephalus. Hydrocephalus does not necessarily cause any disabilities or developmental delays if caught and treated early. My daughter's father was born with hydrocephalus and is a very healthy, athletic 6'3" 44 year old. Mitochondria is a rare condition with little information known so much more unknown. My general understanding is the body is not able to store & metabolize protein. The few known information I've seen states mitochondria comes from the maternal side (I am not sure if they are referring to the condition, disease?) How is it determined that the disabling condition mitochondria (or the lack of mitochondria passed on to the child) comes from the mother? All healthy functional adults have mitochondria, without it we wouldn't be able to do basic daily functions like pick up our toothbrush and brush our teeth. A child's chromosome (DNA) comes from the half paternal and half maternal. How is it the insufficient/weak/mutated/excessive (I don't think excessive is a possible reason for mitochondria) mitochondria does not come from the paternal side and the condition is link with the maternal? Perhaps there's new findings I don't know about but can you please explain what mitochondria condition or is it a disease is? How mitochondria (is only) linked to be contributed from the maternal side?

  4. Need a reviewer for an essay I wrote for extra credit, is this all correct?

    Cells use ATP or Adenosine Triphosphate as their energy currency, but where does it come from? It is created through a process known as cellular respiration consisting of three parts, Glycolysis, the Krebs Cycle, and the electron transport chain. Inside the cell's cytoplasm a Glucose molecule is turned into two Pyruvates and two NADH molecules through a process called glycolysis. Each of those pyruvates are then turned into three NADH molecules and one FADH2 by the Krebs cycle. Next, The NADHs from the Krebs Cycle and Glycolysis along with the FADH2 molecules are deposited inside the Mitochondrial Matrix. There are a set of four Complexes along the inner membrane of the mitochondria that take two electrons from each NADH and each FADH2 and pump out a total of six hydrogen Ions into the Intermembrane space, the area between the inner and outer membranes of the mitochondria. This creates an electrochemical gradient, meaning that those Hydrogen Ions want to get back into the Mitochondrial Matrix. A fifth Complex Lets these hydrogen ions run back through, like water through a water wheel. It uses the energy generated by the movement of the hydrogen ions to put together ADT, or Adenosine Diphosphate with An extra phosphate creating Adenosine Triphosphate, or ATP. The NADHs and FADH2s from one glucose molecule create 34 ATP molecules, as well as two extras as a byproduct of the Krebs cycle and four as byproducts of glycolysis. Take away two because of the initial two ATP spent doing glycolysis and one Glucose Molecule can be turned into 38 ATPs

  5. I'm confused, so if Glycolysis yields 2 NADH and we have two pyruvate that yield 6 NADH through the Kreb's cycle that would be 8 NADH, but Hank says 10 NADH for the electron transport chain, I think I lost track of the numbers

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