Friday, May 7, 2021
Mitochondrial Health

Chromosome (24) mtDNA – Lynn Margulis and the mitochondrial DNA


When we’re born we usually inherit our father’s surname but we also inherit a rather unique type of DNA from our mothers — mitochondrial DNA. Aoife McLysaght explains how this special genetic link can be traced back to the origins of humans, and tells the story of the remarkable female scientist who figured out where our mitochondria came from in the first place.

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43 thoughts on “Chromosome (24) mtDNA – Lynn Margulis and the mitochondrial DNA
  1. from Germ Theory to Gravity, all theories are challenged when proposed, and could be called "slow to gain acceptance." There is no evidence in this video to support the claim that the gender of the scientist was a detriment to her success. 

  2. I've been a fan of Lynn Margulis from first hearing of her ideas (her book Microcosmos written with her son). So, it should be no surprise that I very much like this little video and its presentation and its presenter. Well done!

  3. All humans have mtDNA from one of three haplogroups, conveniently coded L,M,N. The region of intersection of these three groups is southwest Asia. The three women who were the ancestors of these three haplogroups were the three daughters-in-law of Noah.

  4. Feminists and feminism is widely disliked and criticized now because dim-witted social justice warriors (men and women) going around checking their privilege and channeling the guilt of their 'cruel' ancestors into a weird kind of self-flagellation which they just INSIST on sharing with poor unsuspecting (mainly men). If they hate oppression so much why do they get so angry at those who have for whatever reason avoided it. It's these naive, middle class white people going around telling off other middle class white people for not being oppressed, who have brought feminism (at one time a noble cause to get BASIC human rights for women) has now been kidnapped by phony intellectuals and shouty people with very little brain and zero self-awareness. Let's draw a distinction between feminism and SJWs. The ONLY people who like them or listen to them are other SJWs. The general population avoids them, so odious are their childish repetitive diatribes. It is unfair that this woman pointing out the chauvinism of British science back in he day. How many people got the Nobel Prize for DNA? A couple of well connected men. Rosalind Franklin who perfected the special photographic method need to ascertain the shape of DNA did not get any money or recognition. Why? Do we even have to answer it. Sophie Germain, not mentioned on the plaque of scientists who contributed to making the Eiffel Tower. The elasticity of metals is quite important one may imagine in the construction of the Eiffel Tower but lo and behold, not a woman among those names and certainly not hers. Some of you men need to take your head out of your arse and I hate to say it because I sound like Principal PC in South Park, check your privilege.

  5. I know it was a nervous slip, but it is not "a mitochondria", but "a mitochondrion". Also, it wasn't just one proto-animal cell and just one procaryote (blue-green respirating spirochete) that established an endosymbiotic relationship. This happened millions or billions of times due to environmental atmospheric pressures—the era of Stromatolites and infusion of oxygen into the atmosphere 1.5 billion years ago.

    And yes, this is a fact. Mitochondria were once free-living, respiratory, aerobic prokaryotes (true bacteria).  Check out their bacterial chromosome consisting of 16,569 base pairs encoding for 37 genes.

  6. I think mitrocondrial DNA is not fully accurate to trace ancestors, since female usually do not follow men into wars in other nations. At one point, the tracing process will just stuck into same place, same nation. 🤔

  7. Very annoying music. Why should everyone who watches this associate mitochondria haplogroups with that cheery tune? Very poorly thought out and edited. And I was expecting to be told your mother's haplogroup, since it was mentioned at the outset. I would present this crucial information in a much more serious way, not as a factoid. The implications are yet to be uncovered, such as origin of life, or diagnosing hitherto unrecognised genetic illnesses. Serious approach for matters of importance. For anyone reading this, I'd highly recommend Nick Lane's books on the subject.

  8. Ahaa…when did it happen? When the first Eukaryotic cell came into origin? The bacteria was there, already to invade it ! The ONE who was about to make a perfect multicellular organism, intentionally forgot to make a Mitochondira in its basic unit!!!! There are many similaries in the DNA of animals and plants, so what would you say???? I just can't understand how such theories are supported and imposed on genral public. I still don't know how Darwin postulated his evolutionary ideas when he was not even aware of the cell structure!!!!

  9. If only Galileo had had it so easy. Or Einstein and relativity, for that matter.

    It would also be interesting to learn a bio-evolutionary explanation for paternal sur names, which probably stem from property, which, in turn, was a function of male physical dominance in hunter-gatherer societies wherein mothers exchanged certain powers in for protection and a home to raise their offspring. We're also learning that matriarchal hierarchies and social structures in the animal world aren't so gentle (etc.), on land or sea. As for the use of patrilineal surnames, that's a fairly recent practice, and the names were often tied to place or the father's trade. But why "John's son" and not Jane's? Because she was a baby-making cypher.

  10. It's a shame there are so many men who still feel personally attacked when gender biases etc are mentioned. It's a significant part of the picture, it really doesn't need to get your back up. Jesus.

  11. Well i hate to burst your bubble, but a paper published in Nature Genetics 15 in 1996 by Parsons, where a study was done on the substitution rate (mutations) and how often they occured in the mtDNA where they expected to find the "nearest common ancestor" to be about 150,000 y.a.. What he found was that mutations occur much faster and that mtEve was only 6500 yrs old. The "proof' of what you speak is purely deceptive. Because things have the same building blocks to begin with in no way indicates they came from the same thing. How then do you explain the ATP synthase? As you know it produces ATP. But what was required to build such a thing as the ATPsynthase? None other than ATP itself.

  12. Every new scientific thesis undergoes scrutiny. Theories like evolution and gravity were met with doubt by their scientific community of their time and didn’t get the recognition they deserved till much much later and they were men. The idea that it’s because she was a woman proposing a scientific thesis and that’s why she wasn’t immediately praised for her break through is mind numbingly naive. Anyone male or female who proposes a scientific thesis is met with scrutiny.

  13. It took less time for Lynn Margulis theory on mitochondria to be accepted than the time that it took for Barry Marshall to be accepted on his theory of H. pylori causing ulcers. It was peer review that took time not her gender! Even she bristled at the thought that her gender was ever an issue in science.

  14. Y chromosome tracks grandpa to papa to sons to sons to sons to sons … linage all the way from ADAM! — women have no Y genes — and X chromosome in Mitochondria tracks grandma to mama, to daughter, to daughter to daughter all the way from EVE. The goes to prove the Garden of Eden narrative, where EVE was "extracted from ADAM" since he has XY genes and she only XX genes.

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