Monday, September 26, 2022
Mitochondrial Health

#29 Garth Nicolson: How to Repair Mitochondria with Lipid Replacement

Garth Nicolson: How to Repair Mitochondria with Lipid Replacement
The Quantified Body Episode 29 –

This episode includes discussion on:
– Mitochondrial function decline is the underlying problem in many chronic diseases (6:43).
– Mitochondria are the powerhouse of the cell providing energy – like a battery – which fuels the cell’s function (7:43).
– Oxidative damage to the lipid membrane of the mitochondria is the most universal cause of damage (8:38).
– Damage to the lipid membrane harms the phospholipid molecules causing “leakiness” across the membrane (11:30).
– If you don’t produce enough energy in a cell, you lose the function of that cell (13:15).
– Damage to the energy process in a system can occur during aging, chronic illness, viral/bacterial infection, toxic exposure, etc. (13:55).
– Some patients have restored their endocrine systems by repairing their mitochondria in some way (15:53).
– Chronic fatigue illnesses (chronic fatigue syndrome, fibromyalgia, etc.) are directly related to loss of mitochondrial function, which is mostly true for many other diseases as well, such as cancer and neurodegenerative disorders (16:45).
– Much of the mitochondrial function decline occurs because of the natural aging process (18:46).
– For instance, improving the function of a 90 year old, fatigued patient greatly improves mental and physical functions for the patient (19:01).
– Repairing the mitochondrial function for patients who have any of these diseases is not a cure-all, however it is a step in the right direction and definitely supports the overall recovery for the patient (21:21).
– Dr. Nicolson discusses the importance of lipid replacement therapy (LRT) as a way to replace damaged membrane phospholipids to improve mitochondrial function (22:48).
– LRT also functions to detox and repair chemically damaged cells as the lipids delivered to the system can soak any chemicals out from the membranes and remove them from the body (27:11).
– Dr. Nicolson works with populations who have had particular exposures however everyone has been exposed to various chemicals throughout their lifetime (31:05).
– Using both LRT and infrared saunas can speed up the long, slow process of detoxification and recovery (32:47).
– LRT can reduce the symptoms of detoxification and recovery; for example LRT used in conjunction with chemotherapy for cancer patients helps the patient manage the side effects of the cancer treatments (34:50).
– Patients generally see improvement of symptoms between 10 days and 3 months after the start of LRT but when therapy is removed the mitochondrial function declines again and symptoms return (36:39).
– Mitochondrial function can be measured directly by testing the mitochondrial membranes in the white blood cells (38:38).
– LRT is becoming more popular especially with naturopathic doctors and individual people as you do not need a prescription to obtain these natural supplements (40:37).
– An increased dose of lipids is crucial for patients with severe chemical damage or mitochondrial damage so luckily no one has reported negative side effects yet as lipids are natural substances of the body anyways (44:37)!
– Cholesterol markers and homocysteine levels have been shown to improve when using LRT (45:48).
– LRT is proving to be effective as an anti-aging treatment, a therapy for various diseases processes, and as a co-treatment option for cancer patients to reduce negative side effects and fatigue related to traditional therapies (46:29).
– LRT works well at improving energy systems however dosages, etc. do have to be optimized to work with each person’s unique system (50:26).
– LRT is a lifelong solution and a long term treatment because we are constantly exposed to new toxins, infections, and traumas throughout our lives (52:17).
– The minimum supplement needed for LRT is NT factor lipids. (55:32).

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25 thoughts on “#29 Garth Nicolson: How to Repair Mitochondria with Lipid Replacement
  1. I know he said the fats from foods have been damaged. But if I take some olive oil and or organic coconut oil daily would that not repair the cell membranes of cells and mitochondria? Even the least bio-available form of magnesium stopped my muscles spasms from occuring so Im never too sure of these claims saying if its not completely bio-available or if its not my product it won't really do much.

  2. hi, very good interview.
    neurotoxin (heavy doses of fluorine base bbb crosser antibiotic) damage my cns causing Fatal Insomnia (complete inability to sleep) which also damage my mitochondria. Can lipid therapy repair the neuron loss in cns and rewiring the circuicity? here is our group link.
    Please share and spread our group, only four people sufferers gathered by this time. We want to spread the awareness that we are exist and rupture…

  3. Thank you for doing such a good job on the notes to this important video!! I now do not have to watch repeatedly to get all the info:) I just tried NT Factor and ATP Fuel (four days) and I can feel the difference in energy level and clear thinking – looking forward to the full effect. Just subbed!

  4. lipid therapy vs stemcell?
    I believe some toxic damage caused by "hit and run" from toxic exposure such high dose of neurotoxic ingestion/incident. Cells/membrane damage like a bomb attack. Not by accumulation, toxic since toxic washed out by our system after the kill.

  5. Okay…So… (spoiler, don't waste your time)
    Let me summarize: bla bla bla bla bla. Still did not answer the most basic question: what lipids are you talking about.

  6. Don't waste your time with any more quick buck quacks… fat up!

    A lipid technically means a chemical molecule or compound that is not soluble in water. Fatty substances like animal fats and plant oils are made of lipids.
    There are various types of lipids, such as fatty acids, phospholipids, glycolipids, cholesterol, triglycerides, waxes, and steroids.
    Lipids are essential components of skin and play a crucial role in the skin’s barrier function
    (this is a must read – one of the most fundamental concepts in skin
    care). They also play an important role in cell-to-cell signaling.
    The lipids in skin are found in:
    the Stratum Corneum layer of the epidermis – in the stacked lipid bilayers, this is the glue that holds the corneocytes (dead skin cells) together and traps waterthe Granular layer of the epidermis – in the intercellular matrix, here they exist in the form of free fatty acids, cholesterol, and sphingolipids as they are released from lamellar bodies in the keratinocytes that are in the process of breaking down into corneocytescell membranessebum – this is the oil produced by the sebaceous glands attached to follicles
    Because epidermal lipids are so crucial to the skin’s barrier function, the skin barrier is often referred to as the lipid barrier.

    Lipid Damage
    Any kind of damage to lipids has a significant impact on skin because they are so integral to skin health.
    Damage to intercellular lipids weakens the skin’s barrier function. A compromised barrier makes skin more easily irritated and prone to infection. Water loss is also much greater when the lipid barrier is damaged. That water loss leads to dehydrated, flaky, itchy, hot, or burning skin.
    Lipids also make up about 50% of cell membranes.
    This is a large amount, so it’s important to protect them through
    proper care of skin, such as wearing sunscreen and antioxidant products.
    These cell membrane lipids are damaged by free radicals, a process known as lipid peroxidation. When they are attacked by free radicals, they lose their permeability. As a result, nutrients and wastes are transported less efficiently across cell membranes, and the cells become less healthy
    Cell membrane lipids can also be damaged by cross-linking.

    Lipid Composition
    The most effective lipids for skin are the ones that are most identical to the epidermal lipids (the ones in the Stratum Corneum): ceramides (sphingolipids), cholesterol, and fatty acids.
    And the ideal ratio of these lipids is the ratio that they are found in skin, which is roughly:
    50% Ceramides25% Cholesterol25% Fatty Acids
    The lipid composition of sebum, however, is entirely different from the epidermal lipids of the Stratum Corneum. Sebum lipids are composed of approximately:
    30-50% Triglycerides25% Wax Esters15-30% Free Fatty Acids10-15% Squalene4-8% Cholesterol (applause)

  7. NT Factors is made of glycophospholipids, but what are they made of, sugar and PUFAs? If so, how can they be stable being a PUFA, much less healthy to consume?

  8. I think Frank Shallenberger's idea of oxygen utilization, combined with the phospholipid bilayer repair approach, can heal just about every disease, if combined with Gerson and Budwig protocols…. But…who am I ? 🙂

  9. I think he talking about PS and PC… Phosphotidal serine and phosphotidal choline.. one is on the outer membrane, and the PS is on the inner, as I recall… Vitamin E is important for antioxidant activity on our membranes… Phosphotidal choline is lecithin…best to get organic sunflower seed lecithin… PS is found in organ meats, especially… kidneys….yum ! 🙂

  10. PQQ supplement for mitochondrial! Thank you massively for your videos, esp this one. I've suffered with CFIDS & more, with devastating & debilitating after-effects all my life. Subscribed!

    Glad I finally found you!

  11. Cancer is a viral disease. Virus destroys mainly end cells (matured cells in Q
    compartment), to which the organism responds with chronic inflammation and
    increased proliferation to restore the organ and clean the debris. In this
    chronic inflammation tumor may emerge. When stem cells are hit, the entire
    Tissue Proliferation Unit disappears, to which the organism responds with
    dysplasia, carcinoma in situ, carcinoma, etc… According to the hypothesis of
    professor Zajicek MD, tumor protects against cachexia (muscle loss, wasting
    manifested as fatigue and weight loss). Every cure, which silences the disease
    driver, namely virus, cures cancer. Muscle loss is seen in all cancer types.
    Cancer is one disease. Example: Fever is a defensive mechanism. Plus two
    degrees protects while plus five kills. As long as tumor does not block any
    vital function or causes pain, it should be left untreated. Patient should keep
    her tumor as much as possible. Some people find alternative treatments, like
    Ann Vigmor diet, very helpful. With a treatment strategy of tumor dormancy and
    with host resistance to virus , only minimal doses of medication may be
    required. Tumor dormancy is a state:when tumor shrinks or stop growing. In any
    case patient feels healthy.

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