Tuesday, September 21, 2021
Mitochondrial Health

Glycerol-Phosphate Shuttle | NADH, Electron Transport Chain and ATP Yield



Lesson on the Glycerol Phosphate (aka Glycerol-3-Phosphate) Shuttle. NADH produced from glycolysis is unable to enter into the mitochondria because the mitochondrial inner membrane is impermeable and highly selective. Therefore, the cell has to “smuggle” in the protons and electrons from the cytosolic NADH into the electron transport chain, and the cell does this by using the glycerol-phosphate shuttle system.

Hey everyone. In this lesson you will be introduced to the glycerol-phosphate shuttle system. We will discuss in detail why we require this shuttle system, how it operates and how much ATP is generated in the process.

I hope you find this video helpful. If you do, please like and subscribe for more videos like this one. 🙂

JJ

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**MEDICAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in these lessons is for educational purposes ONLY, and information presented here is not to be used as an alternative to a healthcare professional’s diagnosis and treatment of any person/animal.

Only a physician or other licensed healthcare professional are able to determine the requirement for medical assistance to be given to a patient. Please seek the advice of your physician or other licensed healthcare provider if you have any questions regarding a medical condition.

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*Although I try my best to present accurate information, there may be mistakes in this video. If you do see any mistakes with information in this lesson, please comment and let me know.*

I am always looking for ways to improve my lessons! Please don’t hesitate to leave me feedback and comments – all of your feedback is greatly appreciated! 🙂 And please don’t hesitate to send me any messages if you need any help – I will try my best to be here to help you guys 🙂

Thanks for watching! If you found this video helpful, please like and subscribe!
JJ

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13 thoughts on “Glycerol-Phosphate Shuttle | NADH, Electron Transport Chain and ATP Yield
  1. Omg. Thank you. Thank you. Thank you. I have had this surface-level understanding that NADH from glycolysis vs. from the TCA cycle are different in terms of ATP production, but I've never been able to understand it. Until now! Again, THANK YOU!

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