The structure of the matrix-open state of the mitochondrial ADP/ATP carrier allows the determination of its transport mechanism, which involves a rotation around the substrate-binding site. Check out the paper at: http://www.cell.com/cell/fulltext/S0092-8674(18)31517-4.
J.J. Ruprecht, M.S., King, T. Zögg, A.A. Aleksandrova, E. Pardon, P.G. Crichton, J. Steyaert, and E.R.S. Kunji. (2018). The Molecular Mechanism of Transport by the Mitochondrial ADP/ATP Carrier. Cell 176.
And read more great research at http://www.cell.com/cell/home.
5 thoughts on “Energized about the Mechanism of ADP/ATP Transport / Cell, January 24, 2019 (Vol. 176, Issue 3)”
This stimulates so many questions! 👍
MITOCHONDRIA IS THE POWERHOUSE OF THE CELL
Thanks for the wonderful video. I think, after a week of study, I'm BEGINNING to understand ATP/ADP.
I am fearfully and wonderfully made!
just recommended to my year 2 students ; excellent video to accompany a fantastic paper