The structure of the matrix-open state of the mitochondrial ADP/ATP carrier allows the determination of its transport mechanism, which involves a rotation around the substrate-binding site. Check out the paper at: http://www.cell.com/cell/fulltext/S0092-8674(18)31517-4.
J.J. Ruprecht, M.S., King, T. Zögg, A.A. Aleksandrova, E. Pardon, P.G. Crichton, J. Steyaert, and E.R.S. Kunji. (2018). The Molecular Mechanism of Transport by the Mitochondrial ADP/ATP Carrier. Cell 176.
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