Wednesday, October 21, 2020
Mitochondrial Health

Dr. Benjamin Bikman – 'Ketones: The Metabolic Advantage'



Dr. Benjamin Bikman earned his Ph.D. in Bioenergetics and was a postdoctoral fellow with the Duke-National University of Singapore in metabolic disorders. He is currently a professor of pathophysiology and a biomedical scientist at Brigham Young University in Utah.

Dr. Bikman’s professional focus as a scientist and professor is to better understand chronic modern-day diseases, with a special emphasis on the origins and consequences of obesity and diabetes, with an increasing scrutiny of the pathogenicity of insulin and insulin resistance. He frequently publishes his research in peer-reviewed journals and presents at international science meetings.

Dr. Bikman has long been an advocate of a ketogenic diet in light of the considerable evidence supporting its use as a therapy for reversing insulin resistance. His website InsulinIQ.com promotes dietary clarity, healing, and freedom through evidence-based science about insulin resistance. Employing cell-autonomous to whole-body systems, Dr. Bikman’s recent efforts have focused on exploring the intimate associations between the metabolic and immune systems.

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49 thoughts on “Dr. Benjamin Bikman – 'Ketones: The Metabolic Advantage'
  1. Love, Love, Love Dr Bikman. His research is so important. I really hope more people hear what he is saying. Listen to this guy. He has so many important answers to many important questions regarding diseases of modern man.

  2. How can this be explained in evolutionary terms? High insulin signifies a fed state, low insulin a fasting state. You would expect low insulin to correlate to tight coupling in both fat and muscle to preserve stored energy supplies and maximize survival in times of famine. Instead the opposite seems to be the case. Really interesting stuff but a real conundrum, for me at least. I’m a big ketosis diet advocate btw. At 62 I’m returning to the physique I had at 32-magical!

  3. Thanks so much Dr Benjamin this was so amazing and encouraging. Tomorrow is my 24th week on the Carnivore diet and I got sick, massive pain and it took awhile for the drs to realise I had an ovarian cyst and I had such extreme negativity from most of the medical staff about me being in ketosis and of course for being on the Carnivore diet excepting one Doctor who knew of Dr Jason Fung and keto. So this has been uplifting. I've had CFS for a very long time and my muscles had wasted away and now even though I can faint from pain I definitely have so much more physical strength and have amazing muscle tone now. :))))))))

  4. I don't understand this ( 35.24 ) in the evolutionary context. The data says that ketosis makes white fat "browner" which means that it throws more energy away as heat. And ketosis is characteristic of the fasting state, which is what animals go into when there's a famine. But why would an animal throw more energy away during a famine? Surely it makes more sense to conserve energy?

  5. I’m a type 1 diabetic that used to be a sugar burner. I inject all my insulin. The thing that bothers me about “Keto doctors” is that they all tell us we need to avoid insulin. But NONE of them give values for this. Since I inject all my insulin, I know EXACTLY how much insulin I receive each day. But despite this, I’m clueless as to whether that value is good or not. I found one page on the Internet called “understanding type 1 diabetes” saying the daily requirement of insulin for people is their weight in pounds, divided by 4. So I’m 5’ 11” and weigh 180lbs. So it says I should be at 45 units of insulin daily.

    But it doesn’t say how much insulin daily allows me to be in ketosis. And none of the “Keto teachers” actually give values for insulin. Or ACTUAL ways to determine how much insulin a person should receive each day, based on their age/height/weight to be in ketosis.

    If you told me values I should be striving for, I’d be very motivated to hit these values. An example would be…If you needed to be 1/8th of your body weight in insulin each day (so for me 180/8 is 22.5 units of insulin daily). Then I’d actually have a goal in mind that I’d need to hit. Currently on a good day my daily insulin is around 36 units. And I’m slowly improving. But I have no idea what I’m supposed to be striving for.

    I’d be very thankful if you gave values for how much insulin a person can receive each day and still be in ketosis. Because everyone still gets insulin each day, even if they don’t eat food. So how much insulin does a fasting person receive each day.

    I’d be soooooo happy if you (or anyone else knows the answer).

    Also I take 12 units lantus (slow acting insulin) before bed, and 12 units when I wake up. Then I just correct my blood sugar with novolog (fast acting insulin) when it rises above 120. So usually another 12 units of insulin to correct high blood sugars. These numbers all vary by a ton daily.

    Or if anyone could even just tell me their age/height/weight/how much insulin they take each day/and whether they’re in ketosis or not based on those numbers, that would be immensely helpful!!!

  6. the so-called "metabolic advantage" from ketones amounts to a few tens-of cals per day from what I've seen.

    In addition, the inclusion of carbohydrates is more muscle-sparing than ketones.
    FACT

    As well as, the idea of 'flexible dieting' has more positive results than 'rigid dieting'.

    Short answer seems to be.

    Lift heavy, get enough sleep, eat real food, and get enough protein. And do whatever numbers you can manage to keep you in a calorie deficit.
    No need to muck around with ketone-quackery.

  7. Dr. Bikman "s humour us quite dry, but I love it for it's illustrative effect. "I'm sure most of you know exactly what I'm talking about." Ha, I feel spoken to not spoken at I really enjoy the reinforcing nature of his talks!

  8. The over simplifications of every fact,even basic information becomes irritating and at the same time he is patronising to his audience by assuming they have (done their homework)

  9. I don’t understand how NOT eating things designed and processed by men, like bread, pasta, flour, refined sugar, & HFCS, is bad? Lol. God forbid we don’t consume anything that isn’t processed in a factory. It’s so stupid. I’ll never get how people freak out when you say you don’t eat refined carbohydrates. It’s ridiculous. Let’s me know how brainwashed Americans are. How is eating meat, chicken, fish, & eggs, so bad for you? Why do we need carbohydrate? It’s not essential for the body, the body will not die without it. It blows my mind.

  10. Interesting to hear about uncoupling in white fat with ketogenesis. For myself, when I fast, many areas of my body feel considerably warmer — it "feels" like ALL my fat is actually creating heat.

  11. something I don't understand is, why do I have to add so much MORE fat to my diet if I'm already 300 lbs of chewed up blubber and bubble gum — my thought process is.. with the exception of ingesting some omega 3 fatty acids to help reduce bad cholesterol and such my metabolism should use that stored fat; why should I need to supplement my body with additional calories in the form of fats to "burn" (that's, where my mindset, is at )

  12. A celebrity, one of the worlds famous sports scientists, Dr. Tim Noakes is a celebrated author and follower of KETOGENIC diet. Surprisingly and in fact, Noakes hasn’t even succeeded in curing his own diabetes—as he will tell you. He diagnosed himself, based on his blood-sugar levels and family history. Even after a year on the high-fat, low-carb regimen, his fasting glucose had barely budged; it was still hovering above 125. “Nothing happened,” he said. So he prescribed himself metformin, a common first-line diabetes drug. “He was on two grams a day, which is a massive dose.” When that didn’t work, he added supplements, including berberine, curcumin, and one called N-acetyl cysteine. That finally got his glucose and hemoglobin A1c (another marker of diabetes) under control. “So I’m cured,” he says. “But he not cured, because he still has to take the medicine.”
    WHY?
    It is about how many times you eat a day, it doesn't matter what you eat and how much you eat, of course processed foods are a big no and importance of macros cannot be underplayed, OMAD diet and TMAD diet will work and sustainable throughout life. The hormones and calories and carbs and proteins and oils and Keto and extended fasting (think about thin and non obese people) and other lines of discussions are meaningless and confusing. So many proponents for each of them with conflicting stands. Because the reason is not Glucose or Ketones, it is Excess Insulin. Please go through Dr. Joseph R Kraft's videos and his book "Diabetes Epidemic and you" Or go through touchworld.org
    The beauty is we can measure the insulin patterns and reverse diseases by following OMAD and TMAD diets. Almost all diseases, mental and physical are associated with excess insulin! KETOGENIC DIET supresses the Glucose levels in blood, but does not cure the dormant disease. WHAT is this dormant disease? The diabetes as we know is created by Pharma and almost all doctors, health professionals and people are misled, the truth is it is not glucose level that matters, it is Insulin!
    Animal PROTEIN has a high insulin response. The reason they are actually never cured of diabetes, it is only their symptoms of diabetes are supressed. KETO followers are happy with lower glucose levels or lower readings of HbA1C. Wake up friends!
    Dr. Kraft addresses the true disease simply and practically and it is equated with Hyperinsulinemia and measurable. Not only millions of (great) doctors and scientists are mislead, they are looking at plasma glucose levels to determine if you are diabetic, which is totally wrong, they talk of low carb diet/ketogenic or fasting to keep away from glucose. No doubt, a great doctor, Dr. Jason Fung’s 24 hour fasting is nothing but OMAD diet, who is closest to the truth and helps in reducing the chronic high insulin levels in the blood.
    In KETO, PROTEIN has a high insulin response. The reason they are never cured of diabetes, only their symptoms of diabetes are supressed, with lower glucose levels or lower readings of HbA1C. Wake up friends!
    Dr. Kraft has clinical data on 14,000 + people collected over 25 years, as proof on what constitutes TRUE/REAL DIABETES. Obesity, diabetes mellitus, dementia, etc are all symptoms of “Diabetes” as defined by Dr. Kraft, which manifest after 7 to 12 years being hyperinsulinemic. Only One meal a day OMAD or two meals a day TMAD will solve the problem. It works for non obese persons as well, they get CURED of Obesity, Diabetes, Hypertension, etc., and most of the mental and chronic physical ailments.

  13. I’m a big fan but trying to convince friends and family to listen to Ben is defeated by the long intros. Millennials have short attention spans and basically just want to get to the point.

  14. In reference to 5:15.. I thought that ketones in the urine or breath are acitate which only a small part of the ketone. The other parts are not wasted but used or repackaged. Help me understand how that is calories wasted?

  15. Great presentation, what is not clear to me is how can (initial slides: Insulin Slows metabolic rate) a T1 diabetic (Group 1-3) with 23.1mmol of glucose also has 4.5mmol ketones? I thought if one is in ketosis there would be no insulin circulating?

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