41 thoughts on “Fatty Acid (Beta) Oxidation”
I can not thank you enough. My step one is in a few days. I scored like 92 percentile on biochem/biology MCAT, but in med school, pathology is just way more important so I haven't studied biochem that much over the last 4 years. Why don't you charge for your vids? I mean I am glad you don't because sketchy+ U world + B&B + USMLE Rx + pathoma = breaking the bank. Why don't they make a USMLE study bundle package?!
But why does medium chain acyl co DH deffiency cause hyperammonemia?
Hey @Dirty Medicine one thing I think would be helpful in future videos is after going over a topic. Immediately do a couple of questions pertaining to said just covered material. Or provide a hotlink to one of your high yield questions that pertains to the just covered material. As always great job.
perfect for my shelf exam form biochemistry. Thank you tons!!!!!!!!!!!!!!!!!
Wouldnt you get hypoketotic hypoglycemia in MCAD because you arent making acetyl-CoA and hence cant make ketone body synthesis?
I seriously can't thank you enough! you're a lifesaver Dirty
I rarely leave comments but this was extremely helpful and had to say THANK YOU
This channel is undersubscribed. These videos are awesome.
God bless you!
finally understood what I was reading after watching this vid! Thanks! Simple explanation, fast and AWESOME!
is Myopathic CAT-2 deficiency high yield?
Seek Christ Jesus YHVH.
As clear as day now. Many thanks
Love your expression "long amount" (length, quantity) !!
is there no such thing as a 13 carbon fatty acid then?
this man really explained his plain analogy for two minutes?? my guy try to shorten the length video. quality over quantity
couple of things tho
in primary carnitine deficiency, the carnitine cannot be taken up by skeletal and cardiac muscle.
there is also secondary carnitine deficiency, which is secondary to defects in beta oxidation that lead to a built up of acyl carnitine. This acyl carnitine is lost in the urine… and this leads to a carnitine deficiency.
There is also decreased carnitine synthesis in liver disease or in patients using valproic acid (use of this drug reduces renal reabsorption of carnitine)
CPT-II deficiency as you mentioned also effects liver and kidney, other than skeletal muscle. but the form that affects the skeletal muscle is most common and severe. Treatment here includes avoidance of fasting use of high carb diet and supplementation with medium chain fatty acids
plus following the involvement of fatty acyl coA dehydrogenase. Couple of other enzymes are involved like 2 3 enoyl coA hydratase then 3 hydroxy acyl coA dehydrogenase and 3 ketoacyl coA thiolase. An oxidation then a hydration then another oxidation followed by a cleavage
how the hell do u come up with these mneumonics, holy shit . is this the difference between very sucessful and just passing lol
Thank you very much! This video is very helpful
Thank you Dirty
You are amazing!!
So in first aid it says that MCAD is hypoketotic/hypoglycemic but on the video states that MCAD is nonketotic. I just wanted to know how to distinguish between the two?
Why just first aid say MCAD defficiency is hypoketotic hypoglycaemia?
Meanwhile my exam is gonna ask what is the size of a 13 carbon chain fatty acid
Amazing 👏 🙀
Very helpful. Simplifies complex concepts so well. Thank you so much sir. You just saved me going through thousands of lecture slides
This is exactly what I needed
love you, thanks
No words to explain how perfect your videos are🔥
Anyone know what the difference between non-ketotic and hypoketotic hypoglycemia is? Asking for a friend…
i love your videos!!!
Lmao Dirty you said exactly what I've been thinking for all of Dedicated when you were like "the reason why this is high yield is because…well it's just some minutiae you have to memorize" STEP would not be the beast it is if they cut out all the random bullshit
Legend. Thank you so much for your videos. You, the organic chemistry tutor, and khan academy are the first three creators/teachers I will give money to just as a way of saying thank you for helping me achieve my goals in university and beyond. Having high quality upper level education available for free on YouTube will change the world one day. Thanks again to you and your team.
Unreal! Thanks so much!
11:07 Carnitine Transport Summary
this is so great