Thursday, January 21, 2021
Mitochondrial Health

N-Acetylcysteine (NAC) and Mitochondrial Abnormalities By Professor Michael Berk

Professor Michael Berk is an NHMRC Senior Principal Research Fellow and Alfred Deakin Chair of Psychiatry at Deakin University and Barwon Health, where he heads the IMPACT Strategic Research Centre. He holds an Honorary position at both Melbourne and Monash University and is a highly cited researcher with over 800 published papers predominantly in mood disorders. His major interests are in the discovery and implementation of novel therapies, and risk factors and prevention of psychiatric disorders.

Take-Home Points

• Study results show an effect of NAC only in people with severe depression. 

• NAC has no effect on idiopathic pulmonary fibrosis but does improve the quality of life for patients. 

• Complex 1 of the mitochondrial electron transfer chain is dramatically down-regulated in bipolar disorder.

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12 thoughts on “N-Acetylcysteine (NAC) and Mitochondrial Abnormalities By Professor Michael Berk
  1. Long history of schizophrenia in my family, I take multivits, alpha lipoiec acid, and have tried diets , some help a little, just started on nac, I think it’s helping.

  2. Hey Doc, have you looked at magnesium levels in cerebral spino fluids as part of this or considered the impact of supplemental magnesium theronate and melatonin especially at night? The combo at night improves sleep and that can also impact health both physical and mental.

  3. Love what I’m hearing. I agree fatigue is definitely a considerable symptom to a lot of diseases. Just wish diet and fasting and probiotic intake was also included in the mitochondrial cocktail.

  4. thank you ,,you answered my question ,,I was struggle with my x wife for 10 years ,,and lost my family 5 children are struggle NAC would help this long ago thank you doctor once again

  5. Don't they just have more energy during manic because manic is fed by the adrenals going into overdrive? And adrenals make your energy more readily available

  6. Did you know "chronic fatigue" and "chronic fatigue syndrome" (cfs) are different? People with chronic fatigue are exactly that.. chronically tired. People with the syndrome have bodies that basically poison them from the effort of physical activity. Mixing the two is why people think exercise therapy works.. because it works on the people who are chronically fatigued from stress and depression, and not people who are seriously ruined internally by cfs.

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