There are more than 200 different geroprotective compounds. Some of these are already available as supplements, some are in clinical trials and some have FDA approval. Which are my top 5 that I think i most promising in terms of their anti-aging effects (so focusing more on healthspan than lifespan). And note the use of “promising” – there is still much work to be done to better investigate the long-term safety, dose and timings of different supplements which you should always bear in mind.
Anyway, I made this video more for a bit of fun and to make a longer summary video to pull ideas together from multiple previous videos with some new info too! So hope you like it!
Do my top 5 match yours?
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#aging #anti-aging #supplements #nmn #akg
Intro & useful resources – 00:00
Pick #1 – 03:10
Pick #2 – 06:14
Pick #3 – 08:52
Pick #4 – 11:24
Pick #5 – 12:54
Round-up – 15:28
Bonus #1 – 16:10
Bonus #2 – 16:25
Check out @Life Extension Advocacy Foundation rejuvenation road map;
Nature comment – https://www.nature.com/articles/d41586-018-01668-0#:~:text=A%20class%20of%20drugs%20called,muscles%2C%20immune%20system%20and%20more.
AKG news – https://www.buckinstitute.org/news/a-metabolite-produced-by-the-body-increases-lifespan-and-dramatically-compresses-late-life-morbidity-in-mice/
TAME trial – https://www.afar.org/tame-trial
Table I showed – Partridge, L., Fuentealba, M. & Kennedy, B.K. The quest to slow ageing through drug discovery. Nat Rev Drug Discov 19, 513–532 (2020). https://doi.org/10.1038/s41573-020-0067-7
eLife rapamycin – https://doi.org/10.7554/eLife.16351.001
Suggested Brian Kennedy interview (rapamycin)- https://www.lifespan.io/news/brian-kennedy-on-rapamycin-mtor-and-interventions/
Rapamycin Opinion article – Aging (Albany NY). 2019 Oct 15; 11(19): 8048–8067.
Published online 2019 Oct 4. doi: 10.18632/aging.102355
Previous videos of use;
NAD – https://youtube.com/playlist?list=PLnLFbRYd2NGE83BwpXiWbhs2qokuP2TJ5
Icons in intro; “https://www.freepik.com/free-photos-vectors/background”Background vector created by freepik – www.freepik.com