In Episode #59, Dr. Jill Interviews Dr. Eric Gordon on The Cell Danger Response in Chronic Lyme disease. The Cell Danger Response (CDR) is defined in terms of an ancient metabolic response to threat. CDR encompasses inflammation, innate immunity, oxidative stress, and the ER stress response. Abnormal persistence of the CDR lies at the heart of many chronic diseases.
– The Cell Danger Response (CDR) is defined in terms of an ancient metabolic response to threat.
– The CDR encompasses inflammation, innate immunity, oxidative stress, and the ER stress response.
– The CDR is maintained by extracellular nucleotide (purinergic) signaling.
– Abnormal persistence of the CDR lies at the heart of many chronic diseases.
– Antipurinergic therapy (APT) has proven effective in many chronic disorders in animal models.
Dynamic Role of Interleukin-6 in Inflammation: https://www.jillcarnahan.com/2020/09/21/a-fascinating-look-at-the-dynamic-role-of-interleukin-6-in-inflammation/
Tick-Borne Relapsing Fever: https://www.jillcarnahan.com/2021/03/16/tick-borne-relapsing-fever-danger/
What is Metabolic Endotoxemia?: https://www.jillcarnahan.com/2018/04/30/what-is-metabolic-endotoxemia-a-toxic-overload-from-within/
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