#Mitochondria #cellbio #membranedynamics
The mitochondrial matrix is surrounded by two membranes: The OMM and the IMM. The OMM acts as a diffusion barrier and also mediates the transduction of signals into and out of mitochondria. The IMM includes two main sub compartments: the IBM and mitochondrial cristae.
Cristae are connected to the IBM via cristae junctions, which are narrow clefts that close the cristae and thereby prevent the contents of the cristae from being released into the intermembrane space (IMS). Shaping the IMM into cristae depends on various membrane-shaping proteins, including the mitochondrial contact site and cristae organizing system MICOS.