Friday, July 30, 2021
Mitochondrial Health

Krebs cycle | Citric Acid Cycle | Tricarboxylic Acid | CN Sciences

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Thanks for clicking CN Sciences. Today we will discus about Citric Acid Cycle in detail.
The citric acid cycle, shown in —also known as the tricarboxylic acid cycle (TCA cycle) or the Krebs cycle—is a series of chemical reactions used by all
aerobic organisms to generate energy through the oxidation of acetate—derived from carbohydrates, fats, and proteins—into carbon dioxide.
The cycle includes eight major steps.

The function of the citric acid cycle is the harvesting of high-energy electrons from carbon fuels. Note that the citric acid cycle itself neither generates a large amount of ATP nor includes oxygen as a reactant.
The citric acid cycle also produces 2 ATP by substrate phosphorylation from one glucose molecule and plays an important role in the flow of carbon through the cell by supplying precursor metabolites for various biosynthetic pathways. T

The citric acid cycle, also known as the Kreb’s cycle, occurs within the mitochondria of eukaryotic cells and in procaryotic cells, it occurs in the cytosol.

Part of this is considered an aerobic pathway (oxygen-requiring) because the NADH and FADH2 produced must transfer their electrons to the next pathway in the system, which will use oxygen. if oxygen is not present, this transfer does not occur. The citric acid cycle does NOT occur in anaerobic respiration.

End products of citric acid cycle includes two carbon dioxide molecules, one GTP/ATP, three NADH and one FADH2.




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