Monday, May 29, 2023
Mitochondrial Health

Metabolism BOOST With Niacin (Why I Don’t Use NR/NMN)

Metabolism is central to our health. In this video I explain how I use niacin (nicotinic acid) to support my metabolism. I also go through why I currently don’t use either nicotinamide riboside (NR) or nicotinamide mononucleotide (NMN)

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26 thoughts on “Metabolism BOOST With Niacin (Why I Don’t Use NR/NMN)
  1. Any suggestions for timing the niacin? If it spikes blood sugar, is it a good idea to time it with exercise? Do you take it with a meal or on an empty stomach? Any issues with combining it with my morning (quarter dose 1/day) multivitamin which has a complete mix of B vitamins?

  2. Should one take 100-200 mg of Niacin daily for the sake of NAD+ in long run (life time) without any complications (e.g. blood sugar raising or liver failure, etc.) ?

  3. You take only 100mg of Niacin and 500mg of TMG? Does not make sense because TMG is clinically proven to increase cholesterol level (and in fact mine was very high after taking it) Stop taking TMG and switch to sam-e which is also a methyl group donor without side affects.

  4. If you've been taking all these supplements for 30 years, and they've had the desired effect, surely YOUR metabolism won't "fall off a cliff" when you turn 60. You'll have pushed this cliff-falling point out further, won't you?
    If everything is only being held by the thread of continuing to take supplements, and the clock isn't being pushed out into the future at all, then is there any point?

  5. Can you please do a video and research on eye floaters? I'm 57yrs old and my floaters seem to increase as I age. I heard that one of the side effects of taking too much Omega is having floaters. Thanks.

  6. Just wanted to comment on other comments: Regarding flushing, I believe the niacin study referred to in the video used time-release (or non-flushing) version of niacin. As for temporary rise in plasma glucose levels associated with niacin administration – this is not an issue. I know that many who subscribe to ketogenic diets attempt to minimize blood sugar levels. The logic is based on the carbohydrate-insulin theory of obesity – but this has been largely debunked. In addition, studies show that insulin resistance is not driven by sugar but by fat accumulation in certain tissues (e.g., muscle).

  7. I take Niacin with flush 500mg 3 times/dag. When working I take 300 mg morning/lunch and 1000mg after dinner. I do flush sometimes but its mild. I can recommend the book Niacin the true story. Its written by 3 doctors that treat many illness with niacin over the years with flush niacin 1000mg 3 times daily with no side affect. When the persons do not tolerate the flush they used inositol hexanicotinate.
    I also take TMG, B50, D vitamin 50000IU, K2 5mg, magnesium 1000mg, zink 60mg, AKG 1000mg, ashwaganda 1500mg, 30-40ml olive oil, q10, quercetin, blueberryextract, grape, green tea, pinebark, melatonin 6mg at night, GLA 1000mg, berberine/metformin 1000mg. Have surely forget some pills. I feel great.

  8. I caught what you said about high-dose niacin raising blood sugar. I have taken high-dose niacin for years on and off, because it charges up my brain and energizes my body (no time release or flush-free niacin for me, it's gotta have the flush to have the effect), but in my experience taking sugar in any form ruins the effect. Niacin makes me not even want to look at sugar (or eat anything with sugar buried in the ingredients) and actually has caused me to be on a 100% sugar-free diet for a long time. There is some kind of antagonistic or adversarial relationship between niacin and sugar. Maybe raising blood sugar is part of it, but it has to be more complicated than that.

  9. The amino acid L-Serine blocks the the cell receptor sites for a toxic blue-green algae (cyanobacteria) toxin called BMAA, a motoneuron toxin implicated (virtually proven) in ALS, and considered a factor in certain forms of Parkinson's and Alzheimer's. They've also shown that other environmental toxins like mold certain funguses and certain bacteria can also produce neurotoxins. Although I haven't seen whether El serine can block those. I bring those up because of someone that loves seafood you might want to listen to this. They found bmaa and a lot of seafoods including freshwater or saltwater especially coastal regions where they have those bluegreen algae blooms. In stagnant water cyanobacteria is called pond scum.

    If you eat any seafood, you definitely want it research it and consider taking L-serine when you do eat seafood. L-Serine blocks the cell receptor site for the BMAA motoneuron toxin.

    Thanks for your excellent videos! One of the best. Very focused to the point and no fluff!

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