Wednesday, December 1, 2021
Mitochondrial Health

What Causes INSULIN RESISTANCE? [Too Much Fat, or Too Many Carbs]



I answer the good old question: What causes insulin resistance, too much fat, too many carbs, or is there anything else? And as always, I’ll answer the question using science. Everything from research studies to the biochemical side. I fairly compare the two diets, the low fat, high carb, and the low carb high fat diet and their potential to cause insulin resistance, or reverse insulin resistance.

There are 2 main theories about the cause of insulin resistance. Both have as it seems, strong scientific basis, which has a few things in common, and a few facts contradicting each other, which can leave many people confused about the true cause of insulin resistance, resulting in them not knowing what diet and lifestyle should they follow to reverse insulin resistance. After watching this video, you will have a much better understanding of what is insulin resistance, what causes it, and how to reverse it.

So these two main camps are as follows: the first one says that fat causes insulin resistance. And the second says that, that carbs cause insulin resistance. I’ll explain both sides, give you the facts, look at the research, explain the mechanism of each, and let you decide, which one makes more sense to you.

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✦ 𝑹𝑬𝑭𝑬𝑹𝑬𝑵𝑪𝑬𝑺 ✦

Comparison of isocaloric very low carbohydrate/high saturated fat and high carbohydrate/low saturated fat diets on body composition and cardiovascular risk
https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/1743-7075-3-7

Carbohydrate Restriction has a More Favorable Impact on the Metabolic Syndrome than a Low Fat Diet
https://link.springer.com/article/10.1007/s11745-008-3274-2

Comparison of a very low-carbohydrate and low-fat diet on fasting lipids, LDL subclasses, insulin resistance, and postprandial lipemic responses in overweight women
https://pubmed.ncbi.nlm.nih.gov/15047685/

Effect of a ketogenic diet on hepatic steatosis and hepatic mitochondrial metabolism in nonalcoholic fatty liver disease
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132133/

Regulation and Metabolic Significance of De Novo Lipogenesis in Adipose Tissues
https://www.mdpi.com/2072-6643/10/10/1383/htm

Ketogenic diets potentially reverse Type II diabetes and ameliorate clinical depression: A case study
https://pubmed.ncbi.nlm.nih.gov/31336509/

Return of hunger following a relatively high carbohydrate breakfast is associated with earlier recorded glucose peak and nadir
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204795/

Effect of a low-carbohydrate diet on appetite, blood glucose levels, and insulin resistance in obese patients with type 2 diabetes
https://pubmed.ncbi.nlm.nih.gov/15767618/

High-fat diet-induced muscle insulin resistance: relationship to visceral fat mass
https://journals.physiology.org/doi/full/10.1152/ajpregu.2000.279.6.R2057?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org

High dietary fat and sucrose result in an extensive and time-dependent deterioration in health of multiple physiological systems in mice
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900752/

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#insulinresistance #insulinresistancecauses #whatcausesinsulinresistance

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6 thoughts on “What Causes INSULIN RESISTANCE? [Too Much Fat, or Too Many Carbs]
  1. ✦ 𝑹𝑬𝑭𝑬𝑹𝑬𝑵𝑪𝑬𝑺 ✦

    Comparison of isocaloric very low carbohydrate/high saturated fat and high carbohydrate/low saturated fat diets on body composition and cardiovascular risk

    https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/1743-7075-3-7

    Carbohydrate Restriction has a More Favorable Impact on the Metabolic Syndrome than a Low Fat Diet

    https://link.springer.com/article/10.1007/s11745-008-3274-2

    Comparison of a very low-carbohydrate and low-fat diet on fasting lipids, LDL subclasses, insulin resistance, and postprandial lipemic responses in overweight women

    https://pubmed.ncbi.nlm.nih.gov/15047685/

    Effect of a ketogenic diet on hepatic steatosis and hepatic mitochondrial metabolism in nonalcoholic fatty liver disease

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132133/

    Regulation and Metabolic Significance of De Novo Lipogenesis in Adipose Tissues

    https://www.mdpi.com/2072-6643/10/10/1383/htm

    Ketogenic diets potentially reverse Type II diabetes and ameliorate clinical depression: A case study

    https://pubmed.ncbi.nlm.nih.gov/31336509/

    Return of hunger following a relatively high carbohydrate breakfast is associated with earlier recorded glucose peak and nadir

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204795/

    Effect of a low-carbohydrate diet on appetite, blood glucose levels, and insulin resistance in obese patients with type 2 diabetes

    https://pubmed.ncbi.nlm.nih.gov/15767618/

    High-fat diet-induced muscle insulin resistance: relationship to visceral fat mass

    https://journals.physiology.org/doi/full/10.1152/ajpregu.2000.279.6.R2057?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org

    High dietary fat and sucrose result in an extensive and time-dependent deterioration in health of multiple physiological systems in mice

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900752/

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