Thursday, August 11, 2022
Mitochondrial Health

Cell Danger Response in Chronic Illness Eric Gordon interview by Jill Carnahan



Interview of Dr. Eric Gordon on The Cell Danger Response in Chronic Lyme disease by Dr. Jill Carnahan. The Cell Danger Response (CDR) is defined in terms of an ancient metabolic response to threat. CDR encompasses inflammation, innate immunity, oxidative stress, and the ER stress response. Abnormal persistence of the CDR lies at the heart of many chronic diseases.

Highlights
– The Cell Danger Response (CDR) is defined in terms of an ancient metabolic response to threat.
– The CDR encompasses inflammation, innate immunity, oxidative stress, and the ER stress response.
– The CDR is maintained by extracellular nucleotide (purinergic) signaling.
– Abnormal persistence of the CDR lies at the heart of many chronic diseases.
– Antipurinergic therapy (APT) has proven effective in many chronic disorders in animal models.

Dr. Eric Gordon, MD
https://www.gordonmedical.com/team/eric-gordon-m-d/

Dr. Jill Carnahan, MD https://www.jillcarnahan.com

More information on the Robert Naviaux and the Cell Danger Response

Robert Naviaux, PhD – Naviaux Lab: You can find a list of Dr. Naviaux’s papers on his website. https://naviauxlab.ucsd.edu

The Healing Cycle Research:
https://naviauxlab.ucsd.edu/science-item/healing-and-recovery/

Oxidative shielding or oxidative stress? Naviaux RK. J Pharmacol Exp Ther. 2012 Sep;342(3):608-18. PMID: 22700427
https://jpet.aspetjournals.org/content/342/3/608.long

Metabolic features of chronic fatigue syndrome. Naviaux RK, Naviaux JC, Li K, Bright AT, Alaynick WA, Wang L, Baxter A, Nathan N, Anderson W, Gordon E. Proc Natl Acad Sci U S A. 2016 Aug 29. PMID: N/A
https://www.pnas.org/content/113/37/E5472

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