Saturday, October 1, 2022
Mitochondrial Health

ATP Synthesis | Cell Metabolism Part 4 | Macronutrients Lecture 20

ATP synthase harnesses the potential energy of the proton gradient to synthesize ATP. Subscribe to Nourishable at

This video is part 4 of the Cell Metabolism module within a lecture series on the nutrition science of macronutrients.

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Lecture Development, Hosting & Post-Production by Lara Hyde, PhD

Video Production by Robbie Hyde

Opening Motion Graphics by Jay Purugganan

The information in this video is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images and information, contained on or available through this video is for general information purposes only.

Chapter 9 Wardlaw’s Perspectives in Nutrition, 2019 (Editors: Byrd-Bredbenner, Moe, Berning and Kelley, 11th edition)

ATP synthase is a large protein complex that enables protons to enter from the inner membrane space, fall down a slide that causes the complex to turn, and then spits out protons into the matrix. As ATP synthase spins, it brings ADP and a phosphate group in very close proximity, so close that they form a phosphate bond. The potential energy of the proton falling down its concentration gradient into the matrix is transferred into the phosphate bond of ATP.


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