David Sinclair researched specific substances that can improve the activity of sirtuins, such as resveratrol, pterostilbene, nicotinamide (NR) and nicotinamide mononucleotide (NMN). These substances could improve DNA and epigenomic stability, and mitigate aging. NMN seems to be the most promising of these.
What brand of NMN does David Sinclair recommend?
Every morning, David Sinclair takes 1 gram of Nicotinamide Mononucleotide (NMN), often mixed in his yogurt. While Sinclair never shares brand names, we recommended Peak Performance NMN Supplement + Resveratrol or Ultra Health Pharmaceutical Grade NMN.
Can NMN Increase Longevity?
Scientists have studied two such intermediates, nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN), more extensively than others, and the research is encouraging. Several studies indicate that supplementing with these precursors can increase NAD+ levels and prolong the lifespan of yeast, worms, and mice.
What does NMN taste like?
What does Clean NMN™ taste like? Clean NMN™ is 100% pure without flavor or additives. That being said, it has a very slight sour taste to it, however, when placed under the tongue, it is absorbed quickly and the taste dissipates almost instantly.
Does NMN Make You Look Younger?
He said, “Our lab demonstrated that giving NMN to mice over 12 months shows remarkable anti-aging effects.” Translating the results to humans indicates NMN could provide a person with a metabolism of 10 to 20 years younger.
David A Sinclair
David A. Sinclair, Ph.D., A.O. is a Professor in the Department of Genetics and co-Director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School. He is best known for his work on understanding why we age and how to slow its effects. He obtained his Ph.D. in Molecular Genetics at the University of New South Wales, Sydney in 1995. He worked as a postdoctoral researcher at M.I.T. with Dr. Leonard Guarente where he co-discovered a cause of aging for yeast as well as the role of Sir2 in epigenetic changes driven by genome instability. In 1999 he was recruited to Harvard Medical School where he has been teaching aging biology and translational medicine for aging for the past 16 years. Dr. Sinclair is co-founder of several biotechnology companies (Sirtris, Ovascience, Genocea, Cohbar, MetroBiotech, ArcBio, Liberty Biosecurity) and is on the boards of several others. He is also co-founder and co-chief editor of the journal Aging. His work is featured in five books, two documentary movies, 60 Minutes, Morgan Freeman’s “Through the Wormhole” and other media. He is an inventor on 35 patents and has received more than 25 awards and honors including the TIME magazine’s list of the “100 most influential people in the world”.
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