Friday, December 3, 2021
Mitochondrial Health

Characterizing Pathogenic Protein Aggregates for Utilization as Molecular Tools to Accelerate



Presented By: Jacob McPhail, PhD

Speaker Biography: Dr. Jacob A. McPhail is a biochemist with expertise in the structure, function, and regulation of protein complexes. He received his BSc (Hons) in Microbiology and PhD in Biochemistry from the University of Victoria in Canada. His dissertation work focused on the reconstitution of lipid kinases on membranes in vitro to study their regulation and roles in disease. Utilizing a multifaceted approach of hydrogen-deuterium exchange mass spectrometry, X-ray crystallography and cell biology, he explained several mechanisms by which RNA viruses hijack host lipid kinases during infection. Translationally, he aided in the discovery and development of dozens of novel anti-viral, anti-malarial and anti-cancer lipid kinase inhibitors. Dr. McPhail has since applied his biochemistry expertise to neurobiology, specifically investigating the key protein aggregates present in Alzheimer’s and Parkinson’s diseases. He is currently generating and characterizing pathogenic protein oligomers and fibrils in vitro to develop these as novel molecular tools to accelerate neurodegenerative disease research.

Webinar: Characterizing Pathogenic Protein Aggregates for Utilization as Molecular Tools to Accelerate Neurodegenerative Disease Research

Webinar Abstract:

Earn PACE Credits:
1. Make sure you’re a registered member of LabRoots https://www.labroots.com/virtual-event/neuroscience-2021/agenda
2. Watch the webinar on YouTube or on the LabRoots Website https://www.labroots.com/webinar/characterizing-pathogenic-protein-aggregates-utilization-molecular-tools-accelerate-neurodegenerativ
3. Click Here to get your PACE credits (Expiration date – August 25, 2023): https://www.labroots.com/credit/pace-credits/6457/third-party

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