Saturday, May 28, 2022
Mitochondrial Health

Space Destroys Blood Cells And Causes Mitochondria Malfunction



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Hello and welcome! My name is Anton and in this video, we will talk about more health hazards of traveling in space
Links:

https://www.nasa.gov/hrp
https://www.nasa.gov/hrp/bodyinspace
https://pubmed.ncbi.nlm.nih.gov/33242417/
http://www.ohri.ca/newsroom/story/view/1206?l=en
https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.25699
https://en.wikipedia.org/wiki/Mitochondrion
https://www.cell.com/iscience/fulltext/S2589-0042(20)30931-7
https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.25699
https://pubmed.ncbi.nlm.nih.gov/24744266/
https://www.researchgate.net/figure/The-overall-morphology-of-Monocercomonoides-exilis-and-phylogeny-of-Metamonada-a-A_fig1_335023534

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Images/Videos:
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Kelvinsong; modified by Sowlos CC BY-SA 3.0 https://en.wikipedia.org/wiki/Mitochondrion#/media/File:Mitochondrion_structure.svg
Louisa Howard https://en.wikipedia.org/wiki/Mitochondrion#/media/File:Mitochondria,_mammalian_lung_-_TEM.jpg
Javier martin CC BY 2.5 https://en.wikipedia.org/wiki/Microsporidia#/media/File:Fibrillanosema_spore.jpg
Anna Karnkowska, https://www.researchgate.net/figure/The-overall-morphology-of-Monocercomonoides-exilis-and-phylogeny-of-Metamonada-a-A_fig1_335023534

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43 thoughts on “Space Destroys Blood Cells And Causes Mitochondria Malfunction
  1. Ok it’s good to know in detail the effects of space on the human body, but it’s quite evident by now that any farmaceutical strategy won’t solve all the issues. NASA and all other space agencies have to face the reality… either they properly invest in artificial gravity and radiation shielding, or there’s no point in moving forward with lunar or mars human settlings

  2. Has anybody ever done a study on how the magnetic field of earth affects the mitochondria is it possible that it’s not the microgravity that causes long-term damage but the lack of strong magnetic field

  3. Earthlings, terrestrial organisms, are acclimated to life processes within the magnetic field strength at Earth's surface or very near it. If the strength of that field differs or varies significantly in orbit, this might also contribute to the discombobulation terrestrial organisms seem to face there.
    I would expect the electromagnetic effects on our biochemistry to be more significant than the gravitational effects, since the electromagnetic force is so much more powerful than that of gravitation. It may be something as simple as water molecules tending more or less to orient themselves in a certain way than back on Terra firma, which might change the way molecules and even entire cellular structures oriented themselves while suspended in that water.

  4. Are the mitochondria that sensitive to elasticity of space time? We tend to think its us that gravity affects but in reality it's only effecting space and time all around us. In turn we are effected by spacetime.

    Ever hold a cup of coffee while driving? If you were at a resting stop it wouldn't be wise to take off as fast as you can. You might end up with hot coffee all over.

  5. Our products will spread and infest the universe in the new form of evolution of machine rather than the cell evolution that has not allowed that spread out pattern except here on earth.

  6. Really fascinating. The increase in CO from destruction of RBCs is interesting – also implies an increase in HO-1; increases in CO and HO-1 can be a good thing in some contexts (reduction in inflammation). HO-1 exerts effects both through enzymatic activity (through which CO is produced) as well as non-enzymatic activity – it can become localized in the nucleus where is has a role in regulation of transcription. Epigenetic modifications could last a while.
    Another thing to consider is the effect of microgravity on mechanostress in connective tissue which can affect TGF-beta signaling. I think this is why some astronauts experience allergy/atopy problems. This has been attributed to psychological stress; though psychological stress can increase atopic symptoms, IMO its influence has been exaggerated. People with connective tissue disorders such as Marfan syndrome have higher rates of allergy. Low dose doxycycline has been shown to reduce aortic dissection in connective tissue disease models. Losartan has been shown to improve improve TGF beta function Loeys-Dietz syndrome patients.
    Mechanostress also is really important for gut function and I expect that microgravity would cause changes in the gut microbiome, but I don't have time to look it up (yes, I could just do a quick Google search, but then I would be compelled to read the articles and I need to get back to chores).
    Anyway, thanks for this great video and I hope you do more on space medicine.

  7. As the ET Jesus Christ said in the Gospel of Thomas "When you make an eye in place of an eye, a foot in place of a foot, then ye shall enter the kingdom of heaven." We are not quite ready to live in space. We would have to remake ourselves to do that. The result would probably be cyborgs or grey aliens.

  8. Sounds like a centrifuge is a necessary step before going to Mars. You don't want to send astronauts and have them ill on arrival, or worse, suffering more under Mars' weaker gravity. An orbiting cetnrifuge would allow testing the effects of being at earth gravity in space, the change to Mar's gravity, and a prolonged stay at Mars gravity. We could find out how much gravity we need to maintain health. Perhaps it isn't full Earth gravity, which may simplify things a bit. What if something is missing with artificial vs natural gravity? Wouldn't that be weird? A prolonged stay on our Moon would be helpful as well. The need for a centrifuge is so obvious, it's amazing nobody has tested one. I think there might have been a tiny test, but not large enough a human. Bacteria and mice would be good candidates for testing centrifugal gravity. Perhaps a small centrifuge for them inside the ISS could work? That would mean no separate environmental system needed, as if the centrifuge was separate from the ISS. Perhaps a module to test this is in order?

  9. I Respectfully Disagree. Melenated Beings have the ability to be Anywhere in this Universe. This Whole Universe is mostly made up of this Molecule.There was a study on the Black Woman who went to space. When she returned nothing could be found wrong within her. I'm not being a Racist or a Biggot or anything of that Nature. I'm just Here Bringing FACTS.

  10. In the 21st century how do we not have a space station with a centrifuge at least? I always thought humans weren't going to make it in space permanently. Set up a centrifuge like in 2001 or babylon5, otherwise we should just continue with robotic missions, which can yield more info, for a longer period, more safely. Elon will probably terminate space travel anyway though, the Mars idea is likely going to end up a bad day, and even before that happens, one of his satellites is likely to have an accident that will destroy all the others.

  11. Life might have come here with meteorites so if mitochondria are like ancient living fossils with their own DNA, they change perhaps because of such old adaptation mechanism awakening, trying to adapt to a life inside a space rock. Although this suggests they have a way of sensing gravity and that's unlikely I guess.

  12. Astronauts are amazingly brave. Can you picture yourself ever getting on a rocket and launching up into space? Just the thought makes me anxious.

  13. Less diverentional to mantain the thention cicle of the phisicle existence our less darchole intervention inside oll dthe long bladders😍

    Than the aromic watsh has to behave diverendly there too.

    😍

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