Sunday, February 5, 2023
Mitochondrial Health

Mitochondrial Disorders with Alejandro Dorenbaum

To celebrate February as rare disease month we will be interviewing leaders in rare diseases throughout the month! In this episode we explore new research in one of the mitochondrial disorders, primary mitochondrial myopathy (PMM). Joining us for this conversation is Dr. Alejandro Dorenbaum, the Chief Medical Officer of Reneo Pharmaceuticals, who is currently studying an investigational therapy for PMM.

Dr. Dorenbaum is a board-certified allergist-immunologist with over 25 years of experience in drug development and clinical trials. Prior to serving as the CMO of Reneo Pharmaceuticals, he served as the Chief Medical Officer of several other pharmaceutical companies, where he achieved proof-of-concept in clinical trials for novel therapeutic antibodies targeting inflammatory cells. He received his medical degree from the National Autonomous University in Mexico City, and completed his residency in pediatrics at the University of Texas Health Science Center and held fellowship in allergy and immunology at Baylor College of Medicine. He maintains an active academic position as Clinical Professor in Pediatrics at Stanford University School of Medicine.

On This Episode We Discuss:
– The function of the mitochondria
– Challenges of living with a mitochondrial condition
– How primary mitochondrial myopathies (PMM) are unique
– How the percentage of affected mitochondria correlates with the severity of symptoms
– What Reneo doing to help diagnose more patients with PMM
– Reneo’s STRIDE study for treatment of PMM

To learn more about the STRIDE study, check it out at or search for it on Be sure to follow Alejandro on LinkedIn and Reneo Pharmaceuticals on Twitter.

Vizgen is dedicated to pioneering the next generation of genomics, providing tools that demonstrate the possibilities of in situ single cell spatial genomics. These tools are enabling researchers to gain insight into the biological systems that govern human health and disease. Stay tuned for our full episode with Vizgen where we explore single-cell spatial genomics. Get a sneak peak by visiting their website at ​​ Vizgen, leaders in spatially resolved, single-cell transcriptomics. (SPONSORED)

Curious to take a peek inside your body’s drug response? Then you should check out Picture Genetics’ PGx Test. Powered by clinical laboratory Fulgent Genetics, Picture’s PGx Test is easy to order and understand, with hassle-free clinician involvement and good looking reports! Plus you are fully supported through live chats, emails and genetic counseling. To order your Picture PGx test kit use code “DNATODAY” for 25% off and free-shipping! Get actionable genetic insights today to benefit your health tomorrow. (SPONSORED)

PerkinElmer Genomics is a global leader in genetic testing focusing on rare diseases, inherited disorders, newborn screening, and hereditary cancer. Testing services support the full continuum of care from preconception and prenatal to neonatal, pediatric, and adult. Testing options include sequencing for targeted genes, multiple genes, the whole exome or genome, and copy number variations. Using a simple saliva or blood sample, PerkinElmer Genomics answers complex genetic questions that can proactively inform patient care and end the diagnostic odyssey for families. Learn more at (SPONSORED)

Stay tuned for the next new episode of DNA Today on February 11, 2022 where we’ll be discussing Farber disease with Aceragen!

Follow Us On…
Instagram: @DNAradio (
Twitter: @DNApodcast (
Facebook: @DNApodcast (

Listen On…
Spotify (
Apple (…)
Google (…)

DNA Today is a podcast and radio show exploring genetics’ impact on health through conversations with leaders in genetics like genetic counselors, researchers, doctors, and patient advocates. The show started in 2012 and features 170 episodes. DNA Today won the 2020 Best Science and Medicine Podcast Award with nominate four other years.

DNA Today is broadcast every Friday at 10:30am ET on WHUS 91.7 FM in Connecticut. New episodes are released on the first and third Friday of the month with some bonus episodes on other Fridays.

DNA Today is hosted and produced by Kira Dineen. Our social media lead is Corinne Merlino. Our video lead is Amanda Andreoli.


Similar Posts

Leave a Reply

Your email address will not be published.