Sunday, February 5, 2023
Mitochondrial Health

Anti-Aging Interventions, TRT, Cortisol, and How to Fix Your Metabolism with Dr. Kyle Gillett

Is Testosterone Replacement Therapy really a one-size-fits-all treatment? How can you stabilize cortisol levels? We cover it ALL in this episode. In addition to a deep dive on hormonal health, you’ll also get a comprehensive look at cutting-edge longevity practices, and the big levers to repair a broken metabolism.

Today’s guest, Dr. Kyle Gillett, is an M.D. who emphasizes evidence-based treatment medicine, and who believes each patient should be treated holistically. Dr. Gillett utilizes shared decision-making, and a patient-centered approach to meet the needs of each individual’s body, mind, and soul.

You’ll learn:
– Common mistakes made in TRT regiments.
– Six BIG lifestyle interventions that can be immediately implemented.
– What defines cellular aging, and what you can do to optimize cellular health.
– How to balance thyroid and adrenal hormones (plus…a debunk on cortisol confusion).
– A protocol to repair a broken metabolism.

To learn more about Dr. Kyle Gillett, find him on Instagram @kylegillettmd or hear more podcasts with him at

Find the episode guide at If you’re the type of person who enjoys being helpful and adding value, share this episode with someone you know who would benefit from learning these longevity practices.



0:00 Welcome Dr. Kyle Gillett to the show.
1:15 Thank you to show sponsor Organifi.
3:00 Dr. Kyle Gillett’s background and journey into practicing holistic medicine.
6:15 What does a health intervention look like at Dr. Gillett’s office?
10:15 Thyroid health and hormones.
16:00 Stress, hormones, and the adrenal glands.
20:20 Optimizing cellular health.
27:15 Hormone replacement therapy.
31:00 The same prescription for everyone.
34:00 Possible side effects of aromatase inhibitors.
37:20 Why a caloric deficit?
43:50 Detoxification interventions.
47:30 Root cause of acid reflux.
50:30 Obesity medicine and aging.
56:10 Mitochondrial health practices.
1:02:00 What defines cellular anti-aging?
1:06:40 HRV.
1:11:00 Learn more about Dr. Gillett
1:11:45 Thank you again to our sponsor Organifi!


Thank you to our show sponsor Organifi! Shop with code MUSCLE at for 20% off! Organifi offers juice and adaptogenic blend powders, as well as supplements to support immunity, digestion, and detoxification. Everything is certified glyphosate residue free, 100% organic, and free of all major food allergens.

The RED is my recommendation to enhance nitric oxide production, blood flow, and men’s sexual function. The GOLD is my favorite nighttime blend. Organifi also offers a great-tasting GREEN powder, and numerous other adaptogenic products for stress reduction, immune support, digestion, and detoxification. Head over to and shop with code MUSCLE to get 20% off now!


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I’m not in the business of convincing anyone. I’m in the business of transformation.

The individuals who come to us are already high-performers. They’re committed. Ready.

Don’t get me wrong – These guys come with challenges too. They typically have limited time to train, injuries, no gym access, busy families, no customized plans, no specific training knowledge, no coach and an inner fear that it’s going to be too hard.

The only difference between these guys and YOU… is that they took action. They stepped in the ring anyway.

I’m looking for a few more men who want to transform in 2022. If you’re serious and you’re committed, I’d love to see if you’re a right fit for a program I’m starting in 2022. Apply now at


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5 thoughts on “Anti-Aging Interventions, TRT, Cortisol, and How to Fix Your Metabolism with Dr. Kyle Gillett
  1. Phenomenal podcast. I am on a GLP and it did wonders for me. I been on it for a year. Retired BB that became a diabetic. I reversed my diabetes with this and got crazy shredded without a big caloric deficit. My wife said, "I hope your not competing again." So my doc is happy and of course i am. This Doc is what we all need in a family physician. Good stuff!

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