Sunday, September 25, 2022
Mitochondrial Health

Why NMN Is Better than Niacin & NR To Raise NAD Levels | Dr David Sinclair Interview Clips



Dr David Sinclair explains about why NMN is a better molecule to build NAD in our body compare to Niacin, NR and even NAD itself. Also on the effectiveness on taking NMN orally.

David Sinclair is a professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School, where he and his colleagues study sirtuins—protein-modifying enzymes that respond to changing NAD+ levels and to caloric restriction—as well as chromatin, energy metabolism, mitochondria, learning and memory, neurodegeneration, cancer, and cellular reprogramming.

Dr David Sinclair has suggested that aging is a disease—and that we may soon have the tools to put it into remission—and he has called for greater international attention to the social, economic and political and benefits of a world in which billions of people can live much longer and much healthier lives.

Dr David Sinclair is the co-founder of several biotechnology companies (Life Biosciences, Sirtris, Genocea, Cohbar, MetroBiotech, ArcBio, Liberty Biosecurity) and is on the boards of several others.
He is also co-founder and co-chief editor of the journal Aging. He is an inventor on 35 patents and has received more than 35 awards and honors. In 2014, he was on Time Magazine’s list of the “100 Most Influential People in the World,” and listed as Time’s Top 50 in healthcare in 2018.
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DISCLAIMER: Please note that none of the information in this video constitutes health advice or should be substituted in lieu of professional guidance. The video content is purely for informational purposes.

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16 thoughts on “Why NMN Is Better than Niacin & NR To Raise NAD Levels | Dr David Sinclair Interview Clips
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  2. 👍👍💖Thank you! I tried NR one time when I ran out of NMN, I just feel NR didn't have same boosting energy effect as NMN. Now I know why.

  3. I took NMN for some days and I felt so nervous and short of breath, at least 4-5h after taking It (even a very low dosage 50-60mg)… Is it normal? Have you experienced the same?

  4. For some reason, Professor Joseph Baur at the University of Pennsylvania discovered in his studies with mice that NR is taken up in skeletal muscles and the heart more readily than NMN is. He mentions this in the following video: https://youtu.be/xTH3OvoT5wU . So, possibly the smaller molecule passes into these cells more easily.

    Any comment about this assertion?

    edit: Professor Baur makes it clear, in this same video, that both NR and NMN increase NAD+ approximately equally in the non-muscular organs (apart from the brain) such as the liver, the kidneys etc.

  5. What brands, NMN, would you recommend? Renue, sell in capsule and powder. Think one is encased in Lipo to even further protect it from digestive enzymes.

  6. What about the growth of cancer? Is it stimulated by NMN?
    Or precancers or seniscent cells? Will they degenerate to cancer when taking NMN?
    I fear this can ve a very dangerous self-experiment…

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