Fisetin is a flavonoid found in many fruits and vegetables. Fisetin has many benefits, here are 3 major ones. 1) Fisetin is a senotherapeutic that extends health and lifespan. A study from the Lancet, 10 flavonoids including resveratrol, quercetin, curcumin tested, fisetin was the most potent senolytic. 2) Fisetin’s role as an antioxidant – Fisetin works as an antioxidant by protecting cells from free radical damage. It also exhibits anti-inflammatory properties by turning off pathways that promote inflammation and decreasing the production of inflammatory compounds. 3) According to Dr David Sinclair, along with resveratrol and quercetin, fisetin is also a SIRT1 activator. In preclinical trial, fisetin mimics calorie restriction, promote autophagy and increases the levels of AMPK and SIRT1. Fisetin can be obtained from foods and supplements. Let’s count down 10 foods contain fisetin.
David Sinclair is a professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School, where he and his colleagues study sirtuins—protein-modifying enzymes that respond to changing NAD+ levels and to caloric restriction—as well as chromatin, energy metabolism, mitochondria, learning and memory, neurodegeneration, cancer, and cellular reprogramming.
Dr David Sinclair has suggested that aging is a disease—and that we may soon have the tools to put it into remission—and he has called for greater international attention to the social, economic and political and benefits of a world in which billions of people can live much longer and much healthier lives.
Dr David Sinclair is the co-founder of several biotechnology companies (Life Biosciences, Sirtris, Genocea, Cohbar, MetroBiotech, ArcBio, Liberty Biosecurity) and is on the boards of several others.
He is also co-founder and co-chief editor of the journal Aging. He is an inventor on 35 patents and has received more than 35 awards and honors. In 2014, he was on Time Magazine’s list of the “100 Most Influential People in the World,” and listed as Time’s Top 50 in healthcare in 2018.
DISCLAIMER: Please note that none of the information in this video constitutes health advice or should be substituted in lieu of professional guidance. The video content is purely for informational purposes.
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