— Cognitive Impairment and Accelerated Brain Aging: The Insult of Cancer and Cancer Treatments on the Brain
With continued improvements in disease-free survival after cancer treatment, there are increasing numbers of survivors of cancer, currently over 15 million in the US alone with projections for 19 million by 2024 and 26 million by 2040.
During the treatment phase, over 75% of all adult patients complain of cognitive impairment. As long as 10 -20 years after treatment as many as 48% of adult cancer survivors complain of Persistent Fatigue, Depressive Symptoms, Poor Memory and Attention, Difficulty Multitasking, and a Decrease in Executive Functions.
Cancer Related Cognitive Impairment and Fatigue may be severe, persistent and more disruptive than pain and do not resolve with tumor control or treatment cessation. A highly individualized health-focused integrative approach is required to identify functional factors and select appropriate interventions for resolution Chemotherapy, Radiotherapy, Hormonal and Biotherapies as well as cancer biology itself are associated with increases in inflammatory cytokines and reactive oxygen species in the brain. Immune cells, responding to inflammation traverse the blood-brain barrier and increase local inflammation in the brain, affecting emotional and cognitive function. These patients often show loss of grey and white matter and functional and structural changes that resemble accelerated brain aging.
Along with Neuro-inflammation and Neurotoxicity, Myelosuppression, Hepatotoxicity, Nephrotoxicity, Chronic Pain, Microbiome, Endocrine and Sleep Disruption all contribute to Cancer Related Cognitive Impairment. Interventions including Natural Compounds, Acupuncture, Functional Foods, Diet and Lifestyle Modifications and brain rehabilitation therapies can be used to prevent damage and restore function and quality of life to these patients allowing them to return to full and productive lives after treatment.
In this webinar, you’ll learn:
– Describe Effects of Cancer and Cancer Treatments on Cognitive Functions and Brain Aging
– Describe Genetic Factors that increase risk of Cognitive Impairment
– Understand Cancer and Cancer Treatment Related Mechanisms and Effects of Neuro-Toxicity and Neuro-Inflammation
– Understand the use of selected Neuro-protective and Restorative Nutriceuticals, Botanicals and Phytochemicals
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