Tuesday, November 28, 2023
Mitochondrial Health

All You Need to Know About NAD+!

Learn more about the molecule of youth.
What is NAD+?
NAD+ (Nicotinamide adenine dinucleotide) is also referred to as coenzyme. It participates in thousands of enzymatic redox reactions in the human body and is crucial to health and longevity.

The FDA (US Food and Drug Administration) regarding the mechanism, function, and safety of NAD+:
NAD+ has been tested in humans for more than 60 years. Deemed pharmacologically active.
it also has the ability to act efficiently on Sirtuins 1.

This can help relieve fatigue and improve organ health, among many other benefits.

History of NAD+ Research.

NAD+ was first discovered in 1904 by Sir Arthur Harden (1929 Nobel Prize winner in Chemistry).
Two years later, Harden and Yang first described the cellular components of alcohol fermentation as beneficial.

In 1920, von Euler-Chelpin (1929 Nobel Prize winner in Chemistry) first isolated and purified NAD+ and discovered its dinucleotide structure.

In 1930, Otto Warburg (1931 Nobel Prize winner in Medicine) first discovered the key role of NAD as a coenzyme in the metabolism of matter and energy.

Research since 1904
Several Nobel prize-winning scientists have supported NAD+ science.
How NAD+ Functions?

Supplies cells with continuous energy.
NAD+ takes part in human metabolism and generates ATP.
It enhances cell function and replenishes them with energy.

Improves mitochondrial function.
Mitochondria power the cells like a battery.
NAD+ supplementation helps with this energy production by directly improving mitochondrial function.

Effectively activates longevity protein Sirtuins 1-7
The longevity proteins SIRT1-7 regulate ribosomal DNA recombination, participate in gene silencing, DNA repair,
chromosomal stability and may improve longevity. In some cases,
they may prevent disease and reverse aging related illnesses an
d conditions.
Sufficient NAD+ is required to maintain the activity of 7 longevity proteins.

Triggers immune system signals.

NAD+ can modulate the active function of immune cells, such as T cells, and regulate the secretion of interferons and other immune factors.

Repairs DNA.

NAD+ is the only substrate for the DNA repair enzyme PARP,
which is involved in repairing damaged DNA and cells,
reducing the chance of cell mutation and, in some cases, helping prevent cancer.

Awakens and rejuvenates dormant stem cells.

NAD+ can awaken dormant stem cells, such as hematopoietic stem
NAD+ can also reshape stem cells back to their youthful state. cells in the bone marrow.
This can help prevent the degeneration of muscles, skin, and organs.


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