Wednesday, November 29, 2023
Mitochondrial Health

Episode #99: Do You Want More Energy? You Need More of This Compound: Urolithin A

My guest this week is Dr. Singh.

In this episode, Dr. Singh and I discuss a mitochondrial renewal and repair compound, Urolithin A. We talk about the many benefits of Urolithin A such as prolonging life span, increasing muscle function, mitophagy activation and increasing cellular health. Dr. Singh also explains why supplementing Urolithin A can be a whole lot more effective than just eating foods with this compound. So he and his team spent the last decade developing Mitopure. Mitopure is backed by multiple clinical studies and delivers 6X more Urolithin A than diet alone and supports improvements in mitochondrial function and muscle strength.

Learn more about Mitopure at and, use discount code NAT10 for 10% off.

Clinical trial info:


Dr. Singh is currently Chief Medical Officer at Amazentis SA, an advanced nutrition biotech company based in Lausanne, Switzerland that discovers and develops next generation natural compounds targeting improvements in mitochondrial health. In particular, Dr. Singh has designed and led for the last 7 years the clinical development program for the natural mitophagy activator, Urolithin A (Mitopure). This work has led to the commercial launch of several branded consumer health products targeting improvements in cellular health. Dr. Singh received his medical training in Internal Medicine from the Armed Forces Medical College, Pune, India and a PhD in Immunology from the University of Connecticut in USA. He has authored 30 articles in top peer-reviewed journals, holds 10 patents and has designed and led 40 clinical trials over the last 15 yrs.

Follow Dr. Singh

[07:30] About Dr. Singh…

[10:17] How does Urolithin A impact mitochondria?..

[14:38] What are some ways people can trigger mitophagy?..

[19:31] Let’s talk about the gut microbiome…

[31:32] Does Urolithin A cross the blood brain barrier?

[39:11] What is the ideal dosing of Urolithin A?..

[43:15] Would there be a benefit to cycling Urolithin A?..

[48:15] Does dosing vary based on weight, gender or ethnicity?..

[53:00] Does Urolithin A help with fasting?..

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