Mastering Edema with Dr. Najeeb.

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Mastering Edema: Types, Causes, Symptoms & Treatment

Excess fluid in body tissues may be intracellular or extracellular. In defining Edema, if we take out the intracellular, we are still left with “extravascular” & “intravascular”.
Intravascular fluid such as blood plasma will not be included in edema. Therefore, we can define Edema as:
Excess fluid in the body tissues that is present in the Extravascular space.

A normal amount of fluid in a 72kg person would be around 42 liters, and it will be divided among the different body compartments like Intra- & Extracellular.
60% of Total Body Weight is simply water while the remaining 40% can be called Lean Body Mass.
If we want to divide Total Body Water (TBW), we can say:
2/3rd of TBW is Intracellular while 1/3rd is Extracellular.

Extracellular is further divided into Intravascular & Extravascular.
Intravascular is blood plasma. Point to be noted here is that RBCs, platelets & other blood cells have fluid in them and their fluid is classified as Intracellular since it is present within the cells.
Blood plasma on the other hand is not only Intravascular but also, by definition Extracellular.

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