Friday, September 29, 2023
Mitochondrial Health

Could seed oils make you blind? With Chris Knobbe

This week, Paul chats with ophthalmologist and M.D., Chris Knobbe. They continue the conversation about seed oils and they reference observational research to further their point that it is the number one contributor to chronic illness and macular degeneration over sugar.

00:00:00 Podcast begins
00:01:25 Who is Chris Knobbe?
00:04:30 Macular degeneration
00:12:00 How seed oils affect macular degeneration
00:20:30 Carboxymethyl pyrrol
00:27:40 Linoleic acid levels now versus our ancestors
00:45:30 How to avoid seed oils
00:46:10 Seed oils vs. cigarette smoke
00:53:30 Cardiolipin
01:03:00 The problem with studies on linoeic acid
01:09:30 Sugar vs. seed oils

Book: The Ancestral Diet Revolution by Chris Knobbe

Dietary fatty acids and the 10-year incidence of age-related macular degeneration: the Blue Mountains Eye Study:

Heart & Soil:
Carnivore MD Merch:
Make a donation to the Animal Based Nutritional Research Foundation:
Animal-based 30 Challenge:


Similar Posts

43 thoughts on “Could seed oils make you blind? With Chris Knobbe
  1. Can you or anyone on here address nutrivores claims on seed oils. Not only aren’t they inflammatory and bad but good and better than sat fat

  2. Just saw a video from Biolayne. He said a girl who suffers in anorexia contacted him. She was in a clinic where they help people with anorexia and bulemia. They told her to start gaining weight she has to eat carbs and they suggested oatmeal. She started eating it but then she saw this charlatan's video that oatmeal is bad for you and she got scared. Paul doesn't spread knowledge, he spreads misinformation and fear about food. YouTube and social media sites should delete his account like Instagram did before

  3. I am curious about supplementing with Black Seed Oil. People talk a lot about the benefits but it does have a large percentage of linoleic acid. It makes you wonder.

  4. I use sprouted pumpkin seeds to keep my prostate from growing. Maybe the salmon omega 3 will make up for the omega 6 in pumpkin seeds

  5. This is an excellent drill-down on seed oils. Specifically, the time it takes for excess linoleic acid to leave the body, what amount in grams you can safely consume per day and an extra special thing about cancer at almost the very end.

  6. Paul – I think you mentioned you were hoping to have Chris Palmer on soon… Would be awesome if you could discuss potential mitochondrial disrupting effects of LA with him. I know he has thought a lot about excessive carbohydrate load on broken mitochondria but I think he may be missing this part of the picture. Overall a fantastic discussion! I enjoyed the section about Cardiolipin a lot. Keep the podcast nerdy (in a radical way)!

  7. Came here today after listening on SPOT to say I appreciate you having Dr. Knobbe back on. I like listening to him often! Many thanks Dr. Paul πŸ––πŸ½

  8. You should be more concerned about your low Lp(a) levels and what are you going to do about it.
    2012 article title: Low Lipoprotein(a) Concentration Is Associated with Cancer and All-Cause Deaths: A Population-Based Cohort Study (The JMS Cohort Study)

  9. I have so many questions for Dr Knobbe! Please interview him again! I have wet AMD. The puzzling thing is that I have since my early 20s eaten a low processed food diet. I've always made things from scratch. I always used butter and eat plenty of meat. Which is way better than most anyone I know. For the last few years, I do not eat fried anything at a restaurant. I do not even eat out much. Yet here I am, with AMD. The only thing left to do is eat only 100% grass fed and finished beef, pork and chicken fed no grains. That's very expensive.

  10. Paul, if you’re so sure about the deleterious effects of seed oils then go back to school and do a PhD to test your hypotheses. All you do is scare people and sell your supplements! I know so many people that are just scared to eat anything because of people like you. Prove what you’re saying instead of always citing in vitro and animal studies, you hack!

  11. since im barely surviving out here its hard to eat healthy but since paul said "if you can do 1 thing remove seed oils" ive removed seedoils but i still packaged food with additives.
    how bad would you say additives are. I almost think they might be worse than seed oils since they're made from chemicals. but google search usually says these are all "safe".

  12. Other linoleic acid sources, canola oil used to cook at Chipotle, lecithin (70% Linoleic Acid) in smoothies at Jamba Juice and smoothies at grocery stores, Acai juice drinks at Costco, chocolate bars, Mayonaise, salad dressings, some breads, some ice creams, creamers, be suspicious of "natural flavors or ingredients" which are anything from plants or animals, a pass go card for anything the chemists can make from a plant or a animal.

  13. Bring on Simon Hill to the conversation! It's good to hear you are friends, so that your podcast together be a real friendly chat without "debate-tricky-tactics or attacks". Hopefully you guys can define a short list of topics before hand and present your arguments and references to each other with several weeks in advance, ideally with a couple of rounds of interaction, so that no surprising info appears to each other during the podcast recording. I hope you guys agree to do more than just one session. I know this topic "seed oils" have been discussed several times by Simon and his point of view is totally against yours. Another great topic, of course is animal food (or read meat and saturated fat specifically). Both of you seem to have a fantastic diet but, still one is against the other point of view. So probably another great podcast would be discussion of previous 3 years of biomarkers and what would each would suggest to the other to change in order to improve those metrics.

  14. Saw 6 cardiologists ,all said no keto. Red meat is definitely bad,and to watch it over Knives and Netflix. Dad died young and he was fit and on keto . He died exactly the same way as his mom, my grandmother. This time i had to move 5 hours south ,and this cardiologist specializes in valves and internal medicine. My BP was 2 nd stage dangerous, and im 3 months into keto. He said to stop the red meat. Eat chicken and wild fish while i finish the keto,and get back on Mediterranean Diet. He said low carbs cause insulin resistance. I can't win.
    So now i have to wear a holster and have angioplasty. .

  15. Japan's processed food is unfortunately utter garbage.
    When you buy a processed product, it will tend to say "vegetable oil" (怍物油)on the box, so I always assume the worst possible case, e.g. high-linoleic sunflower oil. We used to do this in Norway, but recently the type of oil is usually specified. At least then we can make conscious decisions, e.g. when able to choose between canola or sunflower.
    Sugar is found in most everything – it's very hard to avoid sugar. However, I figure that most people do not actually consume a lot. One contributing factor may be small portion sizes compared to Western countries. You can find a variety of chocolate bars and bags of chocolate at convenience stores with portion sizes of 40-60 grams. They are surprisingly lightweight at times.
    Subjectively, we cannot easily compare Japan to the USA in terms of obesity % in attempting to compare the two countries. If we were to use a BMI of 30+ as a definition of obese, I don't think many Japanese people would qualify. Certainly less than 10%, based on myself recently walking through the streets for about half a year and seeing thousands of people all the time.
    However, that of course does not change the nature of the ongoing metabolic-al disaster πŸ™‚

  16. Really love the discussion on the cardiolipin, electron transport chain and Krebs cycle. Would love a deep dive with the two of you and doctor Ben Lynch.

  17. In my country, many health care advice even said we should eat some unsaturated fat !? and omega-6,omega-3 is good for human. I don't know that theorem came from@@

    but You are doing a great job!! As a consumer,we seems to don't have enough food choice. Maybe it could be a movement to remove seed oil from our life!!πŸ‘πŸ‘

Leave a Reply

Your email address will not be published. Required fields are marked *