CNM-AU8 is an experimental pharmaceutical developed by Clene Nanotherapeutics. It is composed of clean-surfaced gold nanocrystals in pharmaceutical grade water believed to facilitate metabolic activity in the cell. This video explains CNM-AU8, early pre-clinical research, and the results of the VISIONARY-MS phase II trial.
Selected Sources:
ACTRIMS 2023: CNM-Au8 bound for Phase 3 testing after positive data: https://multiplesclerosisnewstoday.com/news-posts/2023/03/01/actrims-2023-cnm-au8-bound-phase-3-testing-after-positive-data/?fbclid=IwAR1cLwATUQd6pfxo3r3zqoX7gYoJKljm7liPVgeDFGgqn4qnvjzdSQhpj00
CNM-Au8 Lessens Vision Problems in RRMS Patients in Phase 2 Trial: https://multiplesclerosisnewstoday.com/news-posts/2022/08/17/clene-therapy-cnm-au8-lessens-vision-problems-ms-trial-rrms/
31P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Multiple Sclerosis. (REPAIR-MS): https://clinicaltrials.gov/ct2/show/NCT03993171
A Multi-Center, Open-Label Long-Term Extension Study of CNM-Au8 In Patients With Stable Relapsing Multiple Sclerosis (VISIONMS-LTE): https://clinicaltrials.gov/ct2/show/NCT04626921
“CNM-Au8 Phase 2 VISIONARY-MS Trial Results: https://invest.clene.com/static-files/bfcceb3c-becc-4ae4-b25e-61697f825713
Clene Announces Updated VISIONARY-MS Phase 2 Trial Data Presented at 2023 ACTRIMS Forum Show CNM-Au8® Demonstrated Significant Improvements in Clinical Outcomes, Brain Structure, and Visual System: https://finance.yahoo.com/news/clene-announces-updated-visionary-ms-120000363.html?guccounter=1&guce_referrer=aHR0cHM6Ly9tdWx0aXBsZXNjbGVyb3Npc25ld3N0b2RheS5jb20v&guce_referrer_sig=AQAAAJLi5usqbAgUse29dl1aOLlA9notuTLC553oYaRhuoi7shOgUNvDKyTt0tJI71lEX9pEZFV89dpeQEozzucewt8GNAdBMKl0pb1KFfE0so6LJ319aTLzp2qalQOgUtBG9ezg28ama69igpFyqafxW2vvG460Am4kYEOFWwOuHt70
Gold-plated Nanocrystals Could Help Fight Multiple Sclerosis: https://news.feinberg.northwestern.edu/2020/03/13/gold-plated-nanocrystals-could-help-fight-multiple-sclerosis/?fbclid=IwAR1i_9xRSgXUKXLZqqWKpkK3v7bTratmhvb9Cl1tMLlrbZ6oqZTwBzoUvNQ
Nanocatalytic activity of clean-surfaced, faceted nanocrystalline gold enhances remyelination in animal models of multiple sclerosis: https://www.nature.com/articles/s41598-020-58709-w
GOLD NANOCRYSTALS MAY BE EFFECTIVE AS ADJUNCTIVE MS THERAPY: https://www.physiciansweekly.com/gold-nanocrystals-may-be-effective-as-adjunstive-ms-therapy/
Study protocol of RESCUE-ALS: A Phase 2, r andomised, double-blind, placebo-controlled study in e arly s ymptomatic amyotrophic lateral sclerosis patients to assess bioenergetic c atalysis with CNM-A u 8 as a mechanism to slow diseas e progression: https://pubmed.ncbi.nlm.nih.gov/33431491/
REPAIR-MS/REPAIR-PD poster: https://invest.clene.com/static-files/c8bebbf5-b9f0-49d4-a1f5-b3b2f7273333
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Dr. Brandon Beaber is a board-certified neurologist with subspecialty training in multiple sclerosis and other immunological diseases of the nervous system. He is a partner in the Southern California Permanente Medical Group and practices in Downey, California (South Los Angeles). He has several publications on MS epidemiology and has participated in clinical trials for MS therapeutics. You can follow him on twitter @Brandon_Beaber where he regularly posts about MS news and research.
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he video material by Dr. Brandon Beaber is general educational material on health conditions and is not intended to be used by viewers to diagnose or treat any individual’s medical condition. Specifically, this material is not a substitute for individualized diagnostic and treatment advice by a qualified medical/health practitioner, licensed in your jurisdiction, who has access to the relevant information available from diagnostic testing, medical interviews, and a physical examination. To the extent that Dr. Beaber endorses any lifestyle change, behavioral intervention, or supplements, the viewer should consult with a qualified healthcare professional to determine the safety and efficacy of the intervention in light of their individualized information.
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Wow! Thank you for the great content again!
I get so excited every Wednesday to see what you are going to be looking at next 😁
Excellent video!
Oh wow
Interested information
Thank you for your work.
you thought mavenclad was expensive… (drinkable golden diamonds for ms)>>>>>hold my beer
Thank you for another great video. Any thoughts on the commercialized NAD+ tru niagen ? Thank you
Can you please comment on PONS therapy?
Fascinating! I wonder if insurance would cover it…. 🤔
Daaaam. Gonna bling out my MS.
Very interesting Ty for sharing and explaining
Gold has always been a natural healer
CNM AU8 I want some
With the boost in ATP, could this be used as a PED? 🤔
I would love to be able to time travel 50-100 years in the future and see where MS research and drug therapies are. I think the most likely progress will be made in STOPPING EBV infection in the first place with a real vaccine (not the mRNA CRAP), and we prevent people from developing MS.
Thanks for explaining this Dr. Beaber. I read about it recently in a newsletter and was hoping it could help repair some damage to the optic nerves. I'm hoping clemastine shows promise as well. I have significant vision loss in one eye, but partial optic atrophy in both due to prior optic neuritis. Uhthoff's makes my vision terrible on a regular basis, so my summer activities are unfortunately very limited. Any treatment that improves vision (even marginally) would be a big win.
Lol, love that line- “YouTube analytics suggests my audience is 0 percent rats and 100 percent humans!” 🙌🏼😂
Your phony wannabe Dr.Burt poison as Ocrevus personal experience 4 plus yrs after 20+ yrs MS only poison as hospitals money only bottom line thieves as Media politicians exterminations false prophets only profits
I shared this trial in a blog when the trial was recruiting. Thank you for sharing the results, really interesting. (It was fun to write, because remyelination is the Holy Grail of MS research; and the fabled Holy Grail is made out of Gold. I made an Indian Jones reference. )
Will be very interesting to see how it fares in the Progressive MS trial. 😊
Thanks for the video. How about a video on coming off DMT after 60 for stable patients. Would you recommend your patients to come off DMT if they are stable at 60 or what would be the criteria.
Thanks for the information. I do have concerns about effects of gold on kidneys. I hope these nano particles will not damage kidneys and won't cause proteinuria…
My mom has Parkinson’s and I have PPMS and I have gotten a lot of similar symptoms she’s gotten 💁♀️
Fascinating video. Thank you.
These studies feel like modern day alchemical wizardry. Kudos to the volunteers . I'm interested in the impact of diet on the process of energy production on the cellular level. I believe the Wahl's diet is based on this theory.
Is this similar to Colloidal Gold?
It's the NAD+ and increasing the energy efficiency in the brain in my opinion, not something exclusive to gold particles. Companies should focus on effects of NAD+, NADH, NMN, NR.
Thank you for the video, Dr. Beaber!
I have a video suggestion for you, I recently came across UCLA’s research that the hormone estriol given to mice with the mouse equivalent of ms promoted myelin repair. Could you do an informational video about the possibility of using estriol to treat ms in women?
Colloidal silver will do the same thing, quite easy to make
Thank you! I prob will not invest yet but willing to try it. There s nothing for DMTs exc immunosuppressives.
Looks like a lot of cherry picking and number wizardry. Great video, well explained as always!
Wow that was interesting…I am looking forward to seeing the second and third trial studies. Thanks for sharing!
“A lot of these things don’t actually PAN out” lol get it, panning for gold…I’ll show myself out.
I guess CNM-AU8 would be a ‘heavy’ treatment, since Au has a high molecular weight
So, with a father with Parkinson's and a daughter with MS, looks like we need to throw a couple of gold ingots in a Vitamix until this drug is approved…
A number of MS drug companies pivoted their studies during the covid pandemic to develop anti-covid drugs. They were chasing the bigger fish…but this meant a lot of existing investors abandoned them as they stopped developing what they promised.
An old lady in my street had MS, said she had coloidal gold, which did her good. She still walked and lived at her own home. She was between 70 and 80 😊.
Just her living like that, gave me sooo much comfort. MS can be calm too.