CNM-AU8 is an experimental pharmaceutical developed by Clene Nanotherapeutics. It is composed of clean-surfaced gold nanocrystals in pharmaceutical grade water believed to facilitate metabolic activity in the cell. This video explains CNM-AU8, early pre-clinical research, and the results of the VISIONARY-MS phase II trial.
ACTRIMS 2023: CNM-Au8 bound for Phase 3 testing after positive data: https://multiplesclerosisnewstoday.com/news-posts/2023/03/01/actrims-2023-cnm-au8-bound-phase-3-testing-after-positive-data/?fbclid=IwAR1cLwATUQd6pfxo3r3zqoX7gYoJKljm7liPVgeDFGgqn4qnvjzdSQhpj00
CNM-Au8 Lessens Vision Problems in RRMS Patients in Phase 2 Trial: https://multiplesclerosisnewstoday.com/news-posts/2022/08/17/clene-therapy-cnm-au8-lessens-vision-problems-ms-trial-rrms/
31P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Multiple Sclerosis. (REPAIR-MS): https://clinicaltrials.gov/ct2/show/NCT03993171
A Multi-Center, Open-Label Long-Term Extension Study of CNM-Au8 In Patients With Stable Relapsing Multiple Sclerosis (VISIONMS-LTE): https://clinicaltrials.gov/ct2/show/NCT04626921
“CNM-Au8 Phase 2 VISIONARY-MS Trial Results: https://invest.clene.com/static-files/bfcceb3c-becc-4ae4-b25e-61697f825713
Clene Announces Updated VISIONARY-MS Phase 2 Trial Data Presented at 2023 ACTRIMS Forum Show CNM-Au8® Demonstrated Significant Improvements in Clinical Outcomes, Brain Structure, and Visual System: https://finance.yahoo.com/news/clene-announces-updated-visionary-ms-120000363.html?guccounter=1&guce_referrer=aHR0cHM6Ly9tdWx0aXBsZXNjbGVyb3Npc25ld3N0b2RheS5jb20v&guce_referrer_sig=AQAAAJLi5usqbAgUse29dl1aOLlA9notuTLC553oYaRhuoi7shOgUNvDKyTt0tJI71lEX9pEZFV89dpeQEozzucewt8GNAdBMKl0pb1KFfE0so6LJ319aTLzp2qalQOgUtBG9ezg28ama69igpFyqafxW2vvG460Am4kYEOFWwOuHt70
Gold-plated Nanocrystals Could Help Fight Multiple Sclerosis: https://news.feinberg.northwestern.edu/2020/03/13/gold-plated-nanocrystals-could-help-fight-multiple-sclerosis/?fbclid=IwAR1i_9xRSgXUKXLZqqWKpkK3v7bTratmhvb9Cl1tMLlrbZ6oqZTwBzoUvNQ
Nanocatalytic activity of clean-surfaced, faceted nanocrystalline gold enhances remyelination in animal models of multiple sclerosis: https://www.nature.com/articles/s41598-020-58709-w
GOLD NANOCRYSTALS MAY BE EFFECTIVE AS ADJUNCTIVE MS THERAPY: https://www.physiciansweekly.com/gold-nanocrystals-may-be-effective-as-adjunstive-ms-therapy/
Study protocol of RESCUE-ALS: A Phase 2, r andomised, double-blind, placebo-controlled study in e arly s ymptomatic amyotrophic lateral sclerosis patients to assess bioenergetic c atalysis with CNM-A u 8 as a mechanism to slow diseas e progression: https://pubmed.ncbi.nlm.nih.gov/33431491/
REPAIR-MS/REPAIR-PD poster: https://invest.clene.com/static-files/c8bebbf5-b9f0-49d4-a1f5-b3b2f7273333
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Dr. Brandon Beaber is a board-certified neurologist with subspecialty training in multiple sclerosis and other immunological diseases of the nervous system. He is a partner in the Southern California Permanente Medical Group and practices in Downey, California (South Los Angeles). He has several publications on MS epidemiology and has participated in clinical trials for MS therapeutics. You can follow him on twitter @Brandon_Beaber where he regularly posts about MS news and research.
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he video material by Dr. Brandon Beaber is general educational material on health conditions and is not intended to be used by viewers to diagnose or treat any individual’s medical condition. Specifically, this material is not a substitute for individualized diagnostic and treatment advice by a qualified medical/health practitioner, licensed in your jurisdiction, who has access to the relevant information available from diagnostic testing, medical interviews, and a physical examination. To the extent that Dr. Beaber endorses any lifestyle change, behavioral intervention, or supplements, the viewer should consult with a qualified healthcare professional to determine the safety and efficacy of the intervention in light of their individualized information.