Friday, September 22, 2023
Mitochondrial Health

This Scientist Believes Pro Cyclists Could Hold The Key To Curing Cancer

Dr Iñigo San Millán is best known as the coach of Tadej Pogačar and for pioneering zone 2 training methods, but did you know he also dedicates a lot of time to cancer research? Si sat down with him at the Tour de France to find out more about how pro cyclists could hold the key to finding a cure for cancer!

00:00 Intro
00:43 Cycling coach & cancer researcher?
02:30 Pioneering cancer research
06:43 Cancer metabolism
08:20 Learning from elite athletes
09:48 Lactate in cancer
14:07 How far along is this research?
16:42 A future cure for cancer?

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29 thoughts on “This Scientist Believes Pro Cyclists Could Hold The Key To Curing Cancer
  1. Not impressed. Sounds dubiously overoptimistic given the decades of years and billions of dollars that have been investigated into understanding cancer and finding treatments. Of course, I am not an expert, but it would be good to get the views of professional cancer researchers who do not spend most of their time coaching bike riders. Both of these interviews, in my view, are some of the weakest products of GCN. It came across like you got a chance to talk to this coach, so why not just talk for a long time about technical science topics, most of which would require fairly advanced biological knowledge to understand properly, as there is lots of jargon and technical biological terms. I am sure that this person is an excellent coach, bringing insights on metabolism to his team, but personally, I'm not at all keen on this type of content for GCN. Sorry to be uniquely disappointed with this, it seems, but I suspect that there are a large number of other AVID GCN fans who would have similar sentiments but not be inclined to write a negative review. Otherwise, of course, GCN is simply amazing, and 99% of the content on youtube and GCN+ is fabulous. Keep that up! Interviews of bike coaches about cancer research. Hmmm – no thanks. At best, dull – at worst, potentially misleading and harmful.

  2. I’m 11 years from my diagnosis of advanced bowel cancer, 2 large tumours, 1 extending beyond the bowel and into the surrounding tissues. I was a keen cyclist before my discovering I had cancer, I regularly rode 80+ miles in the Peak District on Summer Sundays. The day after I was diagnosed I hit the bike and rode as hard as I could though surgery, 6 months of chemotherapy and 2 years of treatment overall. I came out of that time leaner (10+kg lighter) and much faster. Cycling saved me mentally and kept me physically strong.

  3. It is a fact that cancer cells thrive on sugars like glucose and fructose. A lot of what we consume has high amounts of those sugars which for the sedentary person can be potentially dangerous.

  4. I wish Inigo had been my science teacher I would have got top marks, he’s so knowledgable and makes a very complicated subject easy to understand thanks GCN great content 🥰

  5. Very interesting video. However I really struggle to understand exactly how knowledge of these athletes helped to understand anything about the reprogramming of cancer cells towards lactate metabolism. You can't study the energy metabolism in the cells of these athletes. But besides that, the energy metabolism of cancerous cells , like Inigo said, is reprogrammed towards lactate production rather than the Krebs cycle and oxidative phosphorylation like in healthy cells. This difference is between healthy cells and cancerous cells, but how does knowledge from athletes come in handy there? Just really curious what insights were so useful for the researchers.

  6. Absolutely incredible research and show… I am Stage 4 pulmonary adenocarcinoma. (lung cancer) … non smoker.. (for those who judge).. I was originally told that I had 4 months… I am an old roadie, and refused to put my bike down, I have done ten sessions of radiation and 3 series of chemotherapies and one series of immunotherapy, Next month I will be starting a series of directed chemotherapy. I ride. I ride because I still can, my bike has, in my brain kept me alive. I am now ten years into my cancer journey, abused but not beaten. I am certain my bike has kept me going, I understand the words he is saying, but not certain I could use them in a sentence… If blocking lactate is the goal.. why is riding helping me?.. ok.. I am not really producing a lot of lactate (I don't think… I'm 61 years old, one lung and abused… aka not fast, but I do long, long 200+ km rides) Can you shed some light as to what might be going on? I think reducing/ controlling glucose is good… and increasing mitochondrial function… good. But I don't know how much lactate and me have in common. I guess maybe more than I think, my right lung is not functional, the smaller left lung has taken on the task of keeping me upright on the bike.

  7. So interesting and informative, greatly appreciate GCN going a bit beyond the realm of actual cycling. So important to be informed and for true science to be so clearly explained be a real caring expert.
    Thank you GCN!!

  8. Thank you Simon again for the interview with Dr. San Millan. My Biochemistry professors back in the early 90s always told me the regulation of all these pathways is the most important concept to understand. We could not have imagined at the time that these concepts would be a great weapon against cancer. Please continue to have interviews with Dr. San Millan as often as you can. BRILLIANT VIDEO!

  9. I work in this field. I work on mitochondrial function. Very well explained, I have to teach some of this over the next month. About ten years back an opposing tack to blocking lactate was used to enhance mitochondrial function (search DCA). Worked really well on rats, not so well in humans. I have yet to see both approaches used at the same time. I didn't expect to see this topic here, so good job.

  10. The New Doping Era! Lactate Blocking.
    This is why Thibaut Pinaut and David Gaudu wonder how the others don't get tired going full gas Zone 5 for 10 minutes, then back to FTP for other 10 minutes to take a rest.
    Tadej and Rafael Majka have the less lactate concentration in the peloton. UCI can't see this through.

  11. Lance Armstrong's would be a case study. Having had stage 3 cancer which spread to his lungs and brain, although he underwent chemo he is cancer free to date.. Wonder if what is discussed in video was what had help him in his recovery.

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