We talk to Dr Vijay Yadav about some of the results in terms of lifespan and healthspan from the recent paper that he was the main author on.
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Dr Yadav leads the Systems Biology of Aging Laboratory, which aims to identify novel functional connections between organs and to unravel factors that underlie human metabolism and its disorders. The lab’s expertise is in the development of a variety of technologies including mouse genetic (CRISPR/Cas, homologous recombination in embryonic stem cells, iPS cells), genomic (Nucleic acid sequencing), and proteomic (MS/NMR/HPLC). The ultimate aim is to identify novel therapeutic targets for genetic and metabolic disorders to manage these diseases in humans.
00:00 Headline observation
02:40 Taurine decline with age
05:30 Dosing
06:30 Human dosing
09:46 Major biochemical influence
11:53 Senescent cells/Hallmarks of aging
15:38 Systemic effect?
17:08 Inflammation
🌐Links in this video
Dr Yadav on Linkedin _https://www.linkedin.com/in/drvijaykyadav_
Taurine deficiency as a driver of aging _https://www.science.org/doi/10.1126/science.abn9257_
Taurine Caps, Jarrow Formulas 1g _https://iherb.co/a3wg6tsV_
Taurine Powder, Life Extension 300 g _https://iherb.co/a3abpt4M_
*Renue By Science* 10% : _https://tinyurl.com/4yrf4tv3_
Use SUBMHS when buying subscriptions for a continued discount of renewal orders.
*DoNotAge* 10% discount code MODERNHEALTHSPAN _https://tinyurl.com/ycyn9vhn_
*NOVOS* Core & NOVOS Boost $5 off with code MODERNnow5 _https://novoslabs.com/?ref=3957_
*ProHealth* 10% discount code MODERN : _https://prohealth.pxf.io/c/3176409/1541296/17976_
*Bulletproof* 15% off with coupon code: HEALTHSPAN15: _https://tinyurl.com/4npjk5vp_
☕If you would like to support our channel, we’d love a coffee…thank you! _https://www.buymeacoffee.com/mhealthspan_
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Other Supplements that we take
First thing in the morning
Vitamin C 1g – California Gold Nutrition https://iherb.co/tjmJCSKv
D3/K2 – Thorne – https://iherb.co/GYkP4T5b
Life Extension, BioActive, Folate & Vitamin B12, 90 Vegetarian Capsule https://iherb.co/viDytpH
Renue By Science, Liposomal CaAKG 90 300mg capsules – https://tinyurl.com/29j5pfcd
Renue By Science, Lipsomal Glutathione 90 130mg capsules – https://tinyurl.com/yc6dxk34
Equal Exchange, Organic Coffee, French Roast, Whole Bean, 10 oz (283.5 g)
https://iherb.co/hqfF23y
Midday
NOW Foods, TMG, 1,000 mg, 100 Tablets https://iherb.co/hjsroit
Celery Seed, 505 mg, 100 VegCaps https://iherb.co/BvKGp8p2
BioGaia, Osfortis with Vitamin D, 60 Capsules https://iherb.co/wJ14LbC
Celery Seed, 505 mg, 100 VegCaps https://iherb.co/BvKGp8p2
NOW Foods, Turmeric Curcumin, 60 Veg Capsules https://iherb.co/uwHg6SU
California Gold Nutrition, Immune 4, 60 Veggie Capsules (FIRST TIME BUY $1 – LIMITED OFFER)
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California Gold Nutrition, Lutein with Zeaxanthin, 20 mg, 60 Veggie Softgels
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California Gold Nutrition, Astaxanthin, Astaliff® Pure Icelandic, 12 mg, 30 Veggie Softgels https://iherb.co/YqWcvJ3
NOW Foods, Ashwagandha, Standardized Extract, 450 mg, 90 Veg Capsules https://iherb.co/Hv2h2Jz
During the Day
Krill Oil – EPA/DHA – Bullet Proof Krill Oil – https://tinyurl.com/m64fwcsn – Please use code HEALTHSPAN15 at checkout
Bulletproof Innerfuel – https://shop.bulletproof.com/products/innerfuel – Please use code HEALTHSPAN15 at checkout
NOW Foods, Organic Acacia Pure Powder, 12 oz (340 g) https://iherb.co/wyfAnQi
NOW Foods, Psyllium Husk Powder, 12 oz (340 g) https://iherb.co/9kYZ7bg
Evening
Liposomal Apigenin – https://tinyurl.com/3esd726x
Liposomal HLA – https://tinyurl.com/4bhjfwc3
Magnesium Breakthrough – https://bit.ly/3O5tPfu
#taurine #lifespan #vijayyadav
source
Taurine Caps, Jarrow Formulas 1g https://iherb.co/a3wg6tsV
Taurine Powder, Life Extension 300 g https://iherb.co/a3abpt4M
Renue By Science 10% : https://tinyurl.com/4yrf4tv3
Use SUBMHS when buying subscriptions for a continued discount off renewal orders.
DoNotAge 10% discount code MODERNHEALTHSPAN https://donotage.org/ref/modernhealthspan/products
NOVOS Core & NOVOS Boost $5 off with code MODERNnow5 https://novoslabs.com/?ref=3957
ProHealth 10% discount code MODERN : https://prohealth.pxf.io/c/3176409/1541296/17976
Bulletproof 15% off with coupon code: HEALTHSPAN15: https://tinyurl.com/4npjk5vp
Thanks for all your videos and wonderful efforts
6:30 dosing
Don't waste your money supplementing with taurine, just eat more meat because it is a natural occurring chemical inside the meat.
I have seen studies where they speculate that the healthspan and lifespan of the Japanese may be due to the taurine they get from the fish they eat. Same for the okinawan diet.
Also one of the special things in the okinawan diet is their very protein intake ( I think around 9% of calories). So wouldn't one secret in the okinawan diet be a very low protein intake while keeping taurine at a good level?
Glad to know I should keep going as not really experiencing much improvement yet at 1 month.
These sessions with Yadav have been very informative! Please continue.
great questions
Thanks Richard.
Probably true for every amino acid deficiency. So would addressing the deficiency be sufficient or is he recommending mega dosing?
I wonder what the top 3 substances are, that start diminishing in the body after 40. Is there any study on this besides the one on taurine?
1g/Kg dosing? Good God!
In mice… did you read the Peter Attia piece suggesting why it's unlikely to be the same in humans?
Excellent video…thank you!
Has anyone done a sweeping inventory of all the elements of life — e.g., NAD and taurine — that decline with aging?
Seems odds are high that lurking in such a listing might be many hidden gems.