Dr David Sinclair answers about his view on Carbon 60 and it’s potential benefits may relate to mitohormesis.
Back in 1985, Fullerene or Carbon 60 (better known as C60) was discovered and its founding was so monumental to science that the people who discovered it—Robert Curl, Harold Kroto, and Richard Smalley—were awarded the Nobel Prize in Chemistry in 1996. Carbon 60 is a molecule made up of 60 carbon atoms. The layout of the atoms forms a molecule shaped like a soccer ball. Carbon 60 was first used in nanotechnology and electronics. Recently there is interest in using carbon 60 in supplements & medicine. Mitohormesis is a term used to define a biological response where the induction of a reduced amount of mitochondrial stress leads to an increment in health. The activation of the mitohormetic response increases lifespan in different animal models, from worms to mammals. Further, mitohormesis also enhances healthspan, particularly improving metabolism and immune system.
https://pubmed.ncbi.nlm.nih.gov/30072093/
Mitohormesis, an Antiaging Paradigm
https://www.sciencedirect.com/science/article/abs/pii/S0142961212003237
The prolongation of the lifespan of rats by repeated oral administration of [60]fullerene
https://www.sciencedirect.com/science/article/abs/pii/S0278691520301903
Effects of fullerene C60 supplementation on gut microbiota and glucose and lipid homeostasis in rats
David Sinclair is a professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School, where he and his colleagues study sirtuins—protein-modifying enzymes that respond to changing NAD+ levels and to caloric restriction—as well as chromatin, energy metabolism, mitochondria, learning and memory, neurodegeneration, cancer, and cellular reprogramming.
Dr David Sinclair has suggested that aging is a disease—and that we may soon have the tools to put it into remission—and he has called for greater international attention to the social, economic and political and benefits of a world in which billions of people can live much longer and much healthier lives.
Dr David Sinclair is the co-founder of several biotechnology companies (Life Biosciences, Sirtris, Genocea, Cohbar, MetroBiotech, ArcBio, Liberty Biosecurity) and is on the boards of several others.
He is also co-founder and co-chief editor of the journal Aging. He is an inventor on 35 patents and has received more than 35 awards and honors. In 2014, he was on Time Magazine’s list of the “100 Most Influential People in the World,” and listed as Time’s Top 50 in healthcare in 2018.
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DISCLAIMER: Please note that none of the information in this video constitutes health advice or should be substituted in lieu of professional guidance. The video content is purely for informational purposes.
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