The End Of Aging: Part 9 – Mitochondrial Dysfunction

———— ORIGINAL VIDEO ———-

———- HYPERLINKS ———-

Crukih: https://www.youtube.com/channel/UC2Ix9n1V4XPbebxXLNJlghg

Tuldun: https://www.youtube.com/channel/UCOjOCR-0SVIU4b-Flp8bxCQ

Tatoni: https://www.youtube.com/channel/UCEspWHr0j27p3Y-cMNjme1w

Discord: https://discord.com/invite/b6HAZN4

Lifespan discord: https://www.lifespan.io/news/discord-life-extension-server/

———- REFERENCES ———-

Please note, I only have 5000 character for description so I can’t include all references.

The Hayflick limit – https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/hayflick-limit

Aging and evolution – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566834/

Radiocarbon dating of Greenland sharks- https://www.science.org/doi/10.1126/science.aaf1703

Complete anatomy – https://3d4medical.com/

The history of HeLa cells – https://osp.od.nih.gov/hela-cells/significant-research-advances-enabled-by-hela-cells/

Yamanaka factors in mouse embryonic cells – https://www.nature.com/articles/cr2008309

Induced pluripotent cells – https://pubmed.ncbi.nlm.nih.gov/16904174/

Cellular reprogramming – https://clinicalepigeneticsjournal.biomedcentral.com/articles/10.1186/s13148-021-01158-7

Human digit regeneration – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857729/

Regenerative medicine in limb reconstruction – https://www.futuremedicine.com/doi/10.2217/rme-2018-0011

Tooth regeneration – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6987083/

Tooth regrow drug (I could not find the scientific paper for this one) https://mainichi.jp/english/articles/20230609/p2a/00m/0sc/026000c

The 12 hallmarks of aging – https://pubmed.ncbi.nlm.nih.gov/36599349

The rejuvenation roadmap – https://www.lifespan.io/road-maps/the-rejuvenation-roadmap/

A loss of epigenetic information and aging – https://pubmed.ncbi.nlm.nih.gov/36638792/

Genomic instability and aging – https://pubmed.ncbi.nlm.nih.gov/23398157/

DNA replication advances – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117848/

The science behind NMN – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238909/

Telomere length as a biomarker for aging – https://www.frontiersin.org/articles/10.3389/fgene.2020.630186/full

Telomeres and cancer – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370421

Telomerase in cancer – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834434/

Stem cells for human diseases – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357075/

The Horvath clock – https://pubmed.ncbi.nlm.nih.gov/24138928/

The 54% epigenetic rejuvenation paper – https://www.biorxiv.org/content/10.1101/2020.05.07.082917v1.abstract

Proteostasis collapse in cell aging – https://www.pnas.org/doi/10.1073/pnas.1906592116

Cardiac biomarkers – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957084/

Amprion misfolded proteins – https://ampriondx.com/misfolded-proteins/

Grifols and plasma-derived medicine – https://www.grifols.com/en/home

Nutrient sensing and ageing – https://pubmed.ncbi.nlm.nih.gov/30779006/

Sirtuins and ageing – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390530/

Osteoarthritis is pharmaceutically reversible – https://www.nature.com/articles/s41467-023-42199-1

Riordan technologies – https://www.neilriordan.com/

Overview of cell signalling and cell communication – https://www.sciencedirect.com/topics/neuroscience/cell-signaling

Biosplice publications – https://www.biosplice.com/publications/default.aspx

An overview of autophagy – https://www.sciencedirect.com/science/article/abs/pii/S0007455120305014

Autophagy in aging and disease – https://www.nature.com/articles/s43587-021-00098-4

Chronic inflammation and aging – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850851/

Ice baths and chronic inflammation – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350472

Dysbiosis overview – https://www.sciencedirect.com/topics/medicine-and-dentistry/dysbiosis

DALY’S and QALY’s – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819372/

Life without natural causes of death – https://polstats.com/#!/life

Longevity lessons from centenarians – https://www.sciencedirect.com/science/article/pii/S2212066115000022

Longevity escape velocity – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC423155/

WELT Interview with Elon Musk – https://www.youtube.com/watch?v=2WX_mgnAFA0

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