FP HBS Mike Mucciolo takes us through a “First Principles” lesson on the mechanics of sugar and metabolism.
Part 1
0:00 – Intro
0:30 – Disclaimer
0:40 – Sugar, ToW
1:30 – Required Reading
2:00 – ToW, First Principles Thinking
2:40 – Processed Foods and Metabolic Disease
3:30 – Inverse Relationship Between Obesity & Metabolic Disease
3:47 – What is sugar? It’s a carb!
4:46 – Overconsumption leads to weight gain
5:18 – Glucose; The Body’s Primary Fuel Source
6:10 – Blood Sugar
7:15 – The Glycemic Index
8:00 – Grains can be high on the GI
8:33 – Sugar is high mid, considering GL
9:25 – Many fruits are lower glycemic
10:15 – Glucose, Blood Sugar, Fat, and Metabolic Disease
11:22 – FP Grain Article Reference
11:50 – Simple Carbs over Complex Carbs
12:05 – What is a simple vs complex carb
13:28 – Insulin, Blood Sugar, & Glucose
14:00 – Starches
15:18 – Sapiens
Part 2
16:08 – Glycemic Index In context
17:16 – Balanced Blood Sugar & Fitness Propaganda
17:50 – Blood Sugar & Hormone Health
18:40 – Why Fitness Propaganda is Misleading
19:52 – Blood Sugar & Exercise
20:50 – Why Zebras Don’t Get Ulcers
22:00 – Sugar, Metabolism, & Biology
23:09 – Metabolism as a Temperature Regulator
24:48 – Your Thyroid, Hormonal Health, and Stress
27:00 – Making Your Body a Furnace
27:38 – Thyroid & Immune System Health
29:20 – Published Research on Public Health
31:56 – The Faults of Published Research
32:50 – Why Most Published Research Is False
Part 3
34:36 – PUFA’s
35:27 – Ray Peat
36:34 – Beware of Credentialism
37:25 – PUFA’s & Metabolic Health
37:50 – LA Vet’s Hospital Study
40:22 – Mitochondrial Dysfunction & Sugar
41:31 – Fructose
42:30 – Confounding Variables of the demonization of Fructose
46:12 – Possible Thermogenic Effects of Sugar
47:47 – First Principles of Metabolic Health
48:02 – Outro
Have you ever been told to avoid sugar? How did you feel?
If you consider the pro-metabolic properties of glucose,
that may not be such a smart decision…
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