Fatty acid oxidation lecture – This biochemistry lecture explains the process of beta oxidation of fatty acids. This lectures explains the beta oxidation process of fatty acids step by step. beta-oxidation is the catabolic process by which fatty acid molecules are broken down in the cytosol in prokaryotes and in the mitochondria in eukaryotes to generate acetyl-CoA, which enters the citric acid cycle, and NADH and FADH2, which are co-enzymes used in the electron transport to generate ATP molecules.
Beta oxidation of fatty acids takes place in the mitochondrial matrix for the most part. However, fatty acids have to be activated for degradation by coenzyme A by forming a fatty acyl-CoA thioester. For short and medium length fatty acids, they undergo this reaction in the mitochondria.
When pancreatic lipase acts on the small lipid droplets, it breaks them down into free fatty acids and monoglycerides, which are the two digestive products of lipids. These small units are able to pass through the intestinal mucosa and enter the epithelial cells of the small intestine.
Where are fatty acids stored in the body?
Fatty acids are released, between meals, from the fat depots in adipose tissue, where they are stored as triglycerides, as follows: Lipolysis, the removal of the fatty acid chains from the glycerol to which they are bound in their storage form as triglycerides (or fats), is carried out by lapses.
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Thank you for watching the biochemistry lecture on fatty acid oxidation which is also know as the beta oxidation of fatty acids.
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