Let’s discuss how blood sugar issues can accelerate aging.
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—————————————–Show Notes————————————–
0:00 Intro
0:25 Cellular senescence accelerates biologic ageing.
2:00 Senescent cells are enlarged, have dysfunctional mitochondria, and release pro-inflammatory signaling molecules.
2:30 Senescence manifests as wrinkles, memory loss, muscle loss, gray hair, fatty liver, excessive visceral adipose tissue.
3:45 Senescence occurs in response to stressors or developmental signals and behave similar to cancer cells.
5:45 Dysfunctional mitochondria influences glycolysis in cells.
6:15 Give your cells less fuel, glucose, for the proliferation of inflammation.
7:45 Hyperglycemia decreases nitric oxide, which helps prevent cellular senescence.
8:00 Sirtuins can inhibit the formation of senescent cells.
8:55 Berberine, Metformin, and low dose rapamycin, have been used to mitigate hyperglycemia.
10:30 Hyperglycemia also impacts your cardiovascular system and endothelial cells.
12:00 Fat cells can become senescent.
13:00 Ketones (BHB) can help inhibit cellular senescence.
13:25 Optimized omega 3 to omega 6 ratio can help.
14:00 Exercise counters age-related accumulation of senescent cells.
14:40 Senescence within your immune cells is linked with cancer and poor
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