A fertility specialist of Feskov Human Reproduction Group tells about one of the most pressing topics in the scientific world – mitochondrial transfer. This technology allows you to rejuvenate the patient’s egg with the use of donor cytoplasm.
Aleksey Tishchenko has been working as a fertility specialist at the Feskov Human Reproduction Group for over 10 years. His area of responsibility includes embryo cultivation, biopsy, genetic diagnostics, and freezing of biomaterials.
In the video, Aleksey talks about the role of mitochondria in cellular metabolism and how important their functions are in the treatment of infertility.
Borrowing of the cytoplasm in order to obtain the energy of the donor mitochondria is required in those cases when, during cultivation of embryos, the cell division stops at some stage, or the blastocyst stage does not occur. Often, this technology is used in the treatment of infertility in women of late reproductive age (over 40 years old).
One way to implement the method is pronuclear transfer. The fertility specialist tells how it is carried out. The sperm of the future father fertilizes the egg of his wife and in parallel the egg of the donor. Next, the nucleus, which contains the genetic material, is extracted from the donor egg. Instead, the nucleus from the parent egg is placed. Thus, it turns out that the genes of the future embryo are surrounded by a healthy cytoplasm which is able to provide the necessary energy supply to the cell. In this case, the child will receive hereditary information only from his parents.
In the video, Aleksey says that far from at every clinic you can implement this method and get the desired result. The use of this technology at Feskov Human Reproduction Group has become possible thanks to a number of achievements and innovations:
● experience of work in the field of reproductive technologies for more than 20 years;
● use of culture vats of the latest generation with low oxygen content in the chamber;
● use of the Time Lapse system for continuous monitoring of embryo development;
● use of follicle-stimulating hormones of the highest purification in stimulating egg maturation.
The technology of mitochondrial transfer is at the development and research stage, so for its implementation it is necessary to carefully choose the clinic.
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