For more information, see Lin et al., Neuron 94/3, http://www.cell.com/neuron/fulltext/S0896-6273(17)30297-0.
Lin and Cheng et al. reveal a new mechanism maintaining axonal mitochondrial integrity by releasing anchoring protein syntaphilin from static dysfunctional mitochondria. This process enables the removal of dysfunctional mitochondria from axons before activation of Parkin-mediated mitophagy under physiological and pathological conditions.
source
