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This podcast episode features a conversation between Andrew Huberman and Chris Palmer, a medical doctor specializing in psychiatry at Harvard Medical School on the topic of nutrition, diet and mental health. Palmer shares his personal experience with mental illness, which led him to explore the relationship between nutrition and mental health. He discusses how a low-carb or ketogenic diet has a powerful antidepressant effect and how it helped his patients with treatment-resistant mental illness. Palmer also talks about a patient with schizoaffective disorder who experienced a dramatic improvement in his symptoms after following the ketogenic diet. The conversation highlights the importance of frequent contact and making adjustments to medication or nutrition to improve adherence and patient outcomes. They also discuss the historical use of ketogenic diets and fasting to treat epilepsy and how nutrition can be used as a tool to understand and treat mental illnesses. Finally, Palmer explains how the ketogenic diet is effective in improving insulin resistance, lowering glucose levels, and improving insulin signaling.
Timestamp:
Nutrition & Mental Health – 00:27
Low-Carb Diets & Anti-Depression, Fasting, Ketosis 01:13
Schizophrenia, Depression & Ketogenic Diet 01:54
Psychiatric Mediations, Diet Adherence 2:37
Highly Processed Foods, Ketones & Mental Health Benefits 03:29
Ketogenic Diet & Epilepsy Treatment 04:05
Ketogenic Diet & Mitochondria Health. 05:02
Nutrition & Benefits for Neurologic/Psychiatric Disorders. 05:41
Mitochondrial Function & Mental Health 06:39
Mitophagy, Mitochondrial Dysfunction, Aging & Diet 07:15
Neurons, Mitochondria & Blood Glucose 07:57
Obesity, Ketogenic Diet & Mitochondria 08:35
Mitochondrial Function: Inheritance, Risk Factors, Marijuana 09:28
Alcohol & Ketogenic Diet 10:38
Brain Imaging, Alzheimer’s Disease & Ketones 11:30
Exogenous (Liquid) Ketones vs. Ketogenic Diet. 12:05
Neuronal Damage, Ketones & Glucose 12:42
Alzheimer’s Disease, Age-Related Cognitive Decline & Ketogenic Diet 13:26
Ketogenic Diet & Weight Loss 14:28
Ketogenic Diet & Fasting, Hypomania, Sleep 15:06
Low Carbohydrate Diets, Menstrual Cycles, Fertility 15:51
Obesity Epidemic, Semaglutide & GLP-1 Medications 16:35
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