Cellular Signals, Episode 2: “From Foreign to Familiar – The Mitochondrial Saga”
Podcast
Dive into the intriguing tale of mitochondria, the powerhouses of our cells. Once autonomous entities, these cellular components now play a critical role in our energy production. But hints of their foreign origins still linger in our cellular mechanics. In this episode, we unravel the mystery of how an ancient partnership between a proto-eukaryote and a ɑ-proteobacterium laid the foundation for complex life. We’ll explore the delicate dance of biogenesis, xenophagy, and mitophagy, while shedding light on the enduring sense of “foreignness” that our cells retain towards mitochondria. Join us as we trace the evolution of this ancient relationship and discover the remarkable cellular processes that have evolved to maintain this balance.
source
The Alien Within – Mitochondrial origin
