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When mitochondria burn glucose they “fragment” and undergo mutation, causing a rise in ROS and inflammatory cytokines including tgf-beta, the molecular cause of Peyronie’s disease and fibrosis. A ketogenic diet induces “heteroplasmic shifting,” reducing the amount of mutated mitochondria in your body and thereby reducing symptoms of mitochondrial disorders, reducing ROS, tgf-beta, and fibrosis. Moreover, a byproduct of ketosis, beta-hydroxybutatate, blocks tgf-beta, and improves the health of mitochondria. Studies have even shown that a ketogenic diet may have benefits OVER intermittent fasting on mitochondrial health.
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